Vacation Rentals in The Southampton, MO: Compare 10+ Sites & Save

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1041 Best Vacation Rentals in The Southampton (Starting from $44)

Cozy 2BR St. Louis Convenient Loc. Near Downtown
Cozy 2BR St. Louis Convenient Loc. Near Downtown
Apartment
Southhampton, MO, USA
0.7k from The Southampton center

Apartments, Accommodations, Pet-friendly, Lodgings, Places to stay

2 Bedrooms5 Guests
10.0

Exceptional

1 reviews

$138
Average price / night
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Charming bungalow South St Louis : Accessible features!
Charming bungalow South St Louis : Accessible features!
House
St. Louis, MO, 63109, United States
0.1k from The Southampton center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

1 Bedroom3 Guests
New to Booking
$86
Average price / night
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1 bedroom-City Livin
1 bedroom-City Livin
Apartment
Saint Louis, MO, USA
0.8k from The Southampton center

Pet Friendly, Security/Safety, Internet, Parking, Air Conditioner, Guest Services, Fireplace/Heating

1 Bedroom4 Guests
8.5

Very Good

2 reviews

$113
Average price / night
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Picture A City View
Picture A City View
House
St. Louis, MO, 63109, United States
0.5k from The Southampton center

AC, Dryer, Heater, Internet, Kitchen, Laundry, Living Area, Microwave, No Smoking

2 Bedrooms5 Guests
New to Booking
$195
Average price / night
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Urban Chic South City Retreat
Urban Chic South City Retreat
Apartment
Saint Louis, MO, USA
0.8k from The Southampton center

Pet Friendly, Security/Safety, Internet, Parking, Air Conditioner, Guest Services, Fireplace/Heating

1 Bedroom4 Guests
8.0

Good

1 reviews

$127
Average price / night
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South STL City Oasis 2 BR 1 BA Near DT, Forest Park, Wash U, SLU, Blues, City SC
South STL City Oasis 2 BR 1 BA Near DT, Forest Park, Wash U, SLU, Blues, City SC
Apartment
St. Louis, MO, 63109, United States
0.5k from The Southampton center

AC, Dryer, Heater, Internet, Laundry, No Smoking, Washer

2 Bedrooms4 Guests
New to Booking
$153
Average price / night
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Cozy 1-bedroom apartment with free parking
Cozy 1-bedroom apartment with free parking
Apartment
Saint Louis, MO, USA
0.8k from The Southampton center

Pet Friendly, Security/Safety, Internet, Parking, Air Conditioner, Guest Services, Fireplace/Heating

1 Bedroom2 Guests
7.0

Good

6 reviews

$125
Average price / night
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Quiet Safe Neighborhood, Dedicated Office, Easy Hospital Commute, Pet Friendly
Quiet Safe Neighborhood, Dedicated Office, Easy Hospital Commute, Pet Friendly
House
St. Louis, MO, 63109, United States
0.5k from The Southampton center

AC, Dryer, Heater, Internet, Laundry, No Smoking, Washer

2 Bedrooms4 Guests
New to Booking
$66
Average price / night
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South City Pool & Hot Tub 5 Bed
South City Pool & Hot Tub 5 Bed
House
Richmond Heights, MO, USA
0.9k from The Southampton center

Spa, Wellness Facilities, Air Conditioner, Hot Tub, Guest Services, Pool, Internet

10 Bedrooms20 Guests
New to Booking
$1021
Average price / night
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One-bedroom-City Livin'
One-bedroom-City Livin'
Apartment
Saint Louis, MO, 63109, United States
0.6k from The Southampton center

AC, Dryer, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking, TV

1 Bedroom2 Guests
8.2

Very Good

11 reviews

$44
Average price / night
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5733 Tholozan Luxury 2 Bedroom Home With Fenced Backyard
5733 Tholozan Luxury 2 Bedroom Home With Fenced Backyard
House
Richmond Heights, MO, USA
1.0k from The Southampton center

Luxury, Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings

2 Bedrooms6 Guests
10.0

Exceptional

1 reviews

$111
Average price / night
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Historic 2nd Floor Apartment w/ Balcony
Historic 2nd Floor Apartment w/ Balcony
Apartment
Saint Louis, MO, 63109, United States
0.7k from The Southampton center

AC, Balcony, Dryer, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking

1 Bedroom2 Guests
8.6

Fabulous

4 reviews

$111
Average price / night
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Sunny South City Haven 2BR Getaway
Sunny South City Haven 2BR Getaway
House
Lemay, MO, USA
1.1k from The Southampton center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Vacation rentals, Places to stay

2 Bedrooms6 Guests
New to Booking
$148
Average price / night
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Private Gym • 2BR • Modern Condo Downtown
Private Gym • 2BR • Modern Condo Downtown
Apartment
St. Louis, MO, 63109, United States
0.7k from The Southampton center

AC, Heater, Internet, Kitchen, Microwave, No Smoking, TV

2 Bedrooms5 Guests
2.0

Review score

1 reviews

$128
Average price / night
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Blue Door Bungalow | JZ Vacation Rentals
Blue Door Bungalow | JZ Vacation Rentals
House
Southhampton, MO, USA
1.4k from The Southampton center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay, Family, Bungalows

4 Bedrooms10 Guests
New to Booking
$472
Average price / night
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South City Top Floor Apartment
South City Top Floor Apartment
Apartment
St. Louis, MO, 63109, United States
0.7k from The Southampton center

AC, Balcony, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave

1 Bedroom3 Guests
9.6

Exceptional

4 reviews

$106
Average price / night
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4456 Blue Door Bungalow
4456 Blue Door Bungalow
House
Southhampton, MO, USA
1.4k from The Southampton center

Accommodations, Villas, Vacation homes, Cottages, Lodgings, Places to stay, Bungalows

1 Bedroom10 Guests
New to Booking
$431
Average price / night
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Dog-Friendly Apt with Office
Dog-Friendly Apt with Office
Apartment
St. Louis, MO, 63109, United States
0.7k from The Southampton center

AC, Dryer, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking, TV

1 Bedroom3 Guests
8.4

Very Good

8 reviews

$114
Average price / night
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City Chic Retreat!
City Chic Retreat!
Villa
Clifton Heights, MO, USA
2.3k from The Southampton center

Pet Friendly, Parking, Internet, Child Friendly

3 Bedrooms6 Guests
10.0

Exceptional

2 reviews

$108
Average price / night
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Dog-Friendly Apt with King Bed
Dog-Friendly Apt with King Bed
Apartment
St. Louis, MO, 63109, United States
0.7k from The Southampton center

AC, Dryer, Heater, Internet, Kitchen, Microwave, No Smoking, TV, Washer

1 Bedroom3 Guests
9.2

Superb

20 reviews

$111
Average price / night
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Historic First Floor Tower Grove Unit with 4 queen beds STL 1W
Historic First Floor Tower Grove Unit with 4 queen beds STL 1W
House
Clifton Heights, MO, USA
2.3k from The Southampton center

Parking, Security/Safety, Internet, Air Conditioner, Child Friendly

2 Bedrooms8 Guests
New to Booking
$157
Average price / night
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Charming in South Hampton Pets Welcome
Charming in South Hampton Pets Welcome
House
St. Louis, MO, 63109, United States
0.8k from The Southampton center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry

2 Bedrooms4 Guests
10.0

Exceptional

8 reviews

$121
Average price / night
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Central Apt with Office & Balcony
Central Apt with Office & Balcony
Apartment
Saint Louis, MO, 63109, United States
0.8k from The Southampton center

AC, Balcony, Dryer, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking

1 Bedroom2 Guests
8.0

Good

7 reviews

$112
Average price / night
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Spacious St Louis Retreat: 8 Mi to Downtown!
Spacious St Louis Retreat: 8 Mi to Downtown!
House
St. Louis, MO, 63109, United States
0.8k from The Southampton center

AC, Dryer, Fireplace, Free Parking, Heater, Kitchen, Laundry, Living Area, Microwave

3 Bedrooms10 Guests
8.0

Good

1 reviews

$296
Average price / night
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2nd Floor, Brick Duplex near the Hill
2nd Floor, Brick Duplex near the Hill
House
St. Louis, MO, 63109, United States
0.8k from The Southampton center

AC, Balcony, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

2 Bedrooms6 Guests
9.0

Fabulous

46 reviews

$156
Average price / night
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Spacious 2 BR Balcony Hideaway
Spacious 2 BR Balcony Hideaway
Apartment
St. Louis, MO, 63109, United States
0.8k from The Southampton center

AC, Dryer, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking, TV

2 Bedrooms4 Guests
8.0

Good

17 reviews

$119
Average price / night
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Beautiful & Spacious Bungalow - Near Zoo-Downtown
Beautiful & Spacious Bungalow - Near Zoo-Downtown
House
St. Louis, MO, 63139, United States
0.8k from The Southampton center

AC, Balcony, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms8 Guests
10.0

Exceptional

44 reviews

$364
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in The Southampton.

Stay Near The Southampton's Top Attractions

VacationByOwnerRentals can help you find hotels, resorts, and rentals near many of 's top attractions, neighborhoods, and points of interest.

The Southampton Vacation Rentals on the Map

Frequently Asked Questions

You can explore 1041 verified vacation rentals in The Southampton. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in The Southampton vary depending on the season, property size, and location. Rates typically start from around $44 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in The Southampton include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in The Southampton welcome pets. Currently, 65 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in The Southampton often include amenities such as Fireplace/Heating, Pet Friendly, and Wellness Facilities. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.