Vacation Rentals in Santo Domingo, Mexico City: Compare 10+ Sites & Save

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  3.  Mexico

  4.  Mexico City
  5.  Santo Domingo

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2312 Best Vacation Rentals in Santo Domingo (Starting from $22)

A Habitaciones BMR
A Habitaciones BMR
House
Mexico City, Mexico
0.4k from Santo Domingo center

Accommodations, Parking, Homestays, Lodgings, Places to stay

3 Bedrooms8 Guests
6.4

Good

14 reviews

$22
Average price / night
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CIUDAD UNIVERSITARIA GUEST HOUSE
CIUDAD UNIVERSITARIA GUEST HOUSE
House
Ciudad de México, 04369, Mexico
0.1k from Santo Domingo center

Free Parking, Internet, Microwave, TV

2 Bedrooms13 Guests
New to Booking
$116
Average price / night
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B Habitaciones CRT
B Habitaciones CRT
House
Mexico City, Mexico
0.4k from Santo Domingo center

Accommodations, Parking, Homestays, Pet-friendly, Lodgings, Vacation rentals, Places to stay

3 Bedrooms10 Guests
5.7

Review score

17 reviews

$29
Average price / night
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House in Coyoacan ideal for groups and families!
House in Coyoacan ideal for groups and families!
House
Ciudad de México, 04330, Mexico
0.3k from Santo Domingo center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Laundry, Microwave, TV

5 Bedrooms10 Guests
10.0

Exceptional

1 reviews

$219
Average price / night
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CIUDAD DE MEXICO UNAM Guest House Casa de Huespedes
CIUDAD DE MEXICO UNAM Guest House Casa de Huespedes
House
Santo Domingo, Mexico City, Mexico
0.4k from Santo Domingo center

B&bs, Accommodations, Parking, Guest houses, Homestays, Lodgings, Vacation rentals, Places to stay, Accessible hotels

91 Bedrooms55 Guests
7.9

Good

12 reviews

$81
Average price / night
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CIUDAD DE MEXICO UNAM GUEST HOUSE
CIUDAD DE MEXICO UNAM GUEST HOUSE
House
Ciudad de México, 04369, Mexico
0.3k from Santo Domingo center

Free Parking, Internet, TV

1 Bedroom3 Guests
New to Booking
$118
Average price / night
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Habitación Roma
Habitación Roma
House
Mexico City, Mexico
0.4k from Santo Domingo center

Entertainment, Guest Services, Laundry, Parking, Sports/Activities, Security/Safety, Pet Friendly

1 Bedroom3 Guests
8.3

Very Good

15 reviews

$27
Average price / night
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Hermosa Casa estilo Colonial Mexicana en Centro de Coyoacán
Hermosa Casa estilo Colonial Mexicana en Centro de Coyoacán
Villa
Ciudad de México, 04010, Mexico
1.9k from Santo Domingo center

Balcony, Barbecue, Free Parking, Internet, Kitchen, Laundry, No Smoking, Outdoor Space, Patio

5 Bedrooms10 Guests
New to Booking
$1441
Average price / night
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Casa Mexicana
Casa Mexicana
House
Mexico City, Mexico
0.7k from Santo Domingo center

Cheap, Accommodations, Parking, Homestays, Lodgings, Places to stay, Family

3 Bedrooms9 Guests
10.0

Exceptional

5 reviews

$39
Average price / night
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Comfortable Apartment with Internet and 2tv cables near Coyoacand and la Unam
Comfortable Apartment with Internet and 2tv cables near Coyoacand and la Unam
Apartment
Ciudad de México, 04330, Mexico
1.9k from Santo Domingo center

Extra Bed, Laundry, Living Area, Microwave, TV, Washer

2 Bedrooms3 Guests
New to Booking
$74
Average price / night
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UNIVERSIDAD LATINA GUEST HOUSE CASA DE HUESPEDES a
UNIVERSIDAD LATINA GUEST HOUSE CASA DE HUESPEDES a
House
Mexico City, Mexico
0.8k from Santo Domingo center

B&bs, Accommodations, Parking, Guest houses, Homestays, Lodgings, Places to stay

110 Bedrooms81 Guests
8.0

Good

1 reviews

$52
Average price / night
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Living Cerca del Parque de Frida Kahlo, Centro de Coyoacan
Living Cerca del Parque de Frida Kahlo, Centro de Coyoacan
House
CDMX, 04020, Mexico
2.0k from Santo Domingo center

Dryer, Free Parking, Internet, Kitchen, Laundry, Microwave, TV, Washer

6 Bedrooms2 Guests
New to Booking
$899
Average price / night
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Jayau Apartamentos Coyoacan
Jayau Apartamentos Coyoacan
Apartment
Mexico City, Mexico
1.0k from Santo Domingo center

Apartments, Accommodations, Serviced apartments, Lodgings, Places to stay

3 Bedrooms4 Guests
New to Booking
$93
Average price / night
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Room in the heart of Coyoacan, Mexico City
Room in the heart of Coyoacan, Mexico City
House
Ciudad de México, 04010, Mexico
2.0k from Santo Domingo center

Internet, Laundry, No Smoking, Washer

1 Bedroom2 Guests
New to Booking
$70
Average price / night
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Casa en centro de Coyoacán
Casa en centro de Coyoacán
House
Mexico City, Mexico
1.5k from Santo Domingo center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Vacation rentals

5 Bedrooms11 Guests
9.4

Superb

17 reviews

$129
Average price / night
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Amazing French Mansion in the heart of Coyoacan
Amazing French Mansion in the heart of Coyoacan
House
México D.F., 04000, Mexico
2.0k from Santo Domingo center

AC, Arcade, Balcony, Breakfast Available, Dryer, Fireplace, Free Parking, Heater, Hot Tub

11 Bedrooms23 Guests
10.0

Exceptional

3 reviews

$5132
Average price / night
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Departamento con Balcón Coyoacán
Departamento con Balcón Coyoacán
Apartment
Mexico City, Mexico
1.6k from Santo Domingo center

Apartments, Accommodations, Parking, Lodgings, Vacation rentals, Places to stay

3 Bedrooms4 Guests
1.0

Review score

1 reviews

$89
Average price / night
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1 bedroom apartment equipped coyoacan on a 1st floor
1 bedroom apartment equipped coyoacan on a 1st floor
Apartment
Ciudad de México, 04010, Mexico
2.0k from Santo Domingo center

Fitness Equipment, Free Parking, Internet, Kitchen, Microwave, No Smoking, Outdoor Space, Patio, TV

1 Bedroom2 Guests
10.0

Exceptional

1 reviews

$75
Average price / night
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Habitaciones Coyoacan (UNAM)
Habitaciones Coyoacan (UNAM)
House
Mexico City, Mexico
1.7k from Santo Domingo center

B&bs, Cheap, Accommodations, Guest houses, Homestays, Pet-friendly, Lodgings, Vacation rentals, Places to stay

5 Bedrooms15 Guests
9.0

Fabulous

100 reviews

$68
Average price / night
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Villa Coyoacan Colonial
Villa Coyoacan Colonial
House
12 Cjon. del Horno Santa Catarina, Mexico City, 04010, Mexico
2.1k from Santo Domingo center

Free Parking, Internet, Laundry, Soundproof Room

1 Bedroom2 Guests
7.0

Good

10 reviews

$117
Average price / night
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Rincón Raíz
Rincón Raíz
House
Mexico City, Mexico
1.8k from Santo Domingo center

Cheap, Accommodations, Homestays, Lodgings, Places to stay, Family, Self-catering

1 Bedroom2 Guests
10.0

Exceptional

2 reviews

$46
Average price / night
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APARTMENT OF 3 BEDROOMS AND 2 BATHROOMS
APARTMENT OF 3 BEDROOMS AND 2 BATHROOMS
Apartment
Ciudad de México, 04010, Mexico
2.1k from Santo Domingo center

Fitness Equipment, Free Parking, Internet, Kitchen, Laundry, Microwave, No Smoking, Outdoor Space, Patio

3 Bedrooms4 Guests
New to Booking
$71
Average price / night
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Apartment with 2 bedrooms and 2 bathrooms
Apartment with 2 bedrooms and 2 bathrooms
Apartment
Ciudad de México, 04010, Mexico
2.1k from Santo Domingo center

Free Parking, Internet, Kitchen, Laundry, Microwave, No Smoking, Outdoor Space, Patio, TV

2 Bedrooms3 Guests
New to Booking
$63
Average price / night
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Studio Penthouse in floor 32 in south Mexico City. Breathtaking view!
Studio Penthouse in floor 32 in south Mexico City. Breathtaking view!
Apartment
Mexico City, 04700, Mexico
2.1k from Santo Domingo center

Arcade, Dryer, Elevator, Fitness Equipment, Free Parking, Hot Tub, Internet, Kitchen, Laundry

2 Bedrooms4 Guests
New to Booking
$87
Average price / night
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Honey Loft
Honey Loft
Apartment
Ciudad de México, 04000, Mexico
2.2k from Santo Domingo center

Dryer, Internet, Laundry, No Smoking, Washer

1 Bedroom2 Guests
New to Booking
$167
Average price / night
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Departamento en el Corazón de la Condesa
Departamento en el Corazón de la Condesa
Apartment
Ciudad de México, 06140, Mexico
2.2k from Santo Domingo center

Dryer, Internet, Kitchen, Laundry, Washer

3 Bedrooms8 Guests
New to Booking
$311
Average price / night
Check Availability
House with 24 hrs. security 4 km from the Azteca Stadium
House with 24 hrs. security 4 km from the Azteca Stadium
House
Ciudad de México, 04610, Mexico
2.2k from Santo Domingo center

3 Bedrooms7 Guests
New to Booking
$841
Average price / night
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Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in Santo Domingo.

Stay Near Santo Domingo's Top Attractions

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Santo Domingo Vacation Rentals on the Map

Frequently Asked Questions

You can explore 2312 verified vacation rentals in Santo Domingo. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in Santo Domingo vary depending on the season, property size, and location. Rates typically start from around $22 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in Santo Domingo include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in Santo Domingo welcome pets. Currently, 24 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in Santo Domingo often include amenities such as Laundry, Internet, and Kitchen. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.