Vacation Rentals in Santa Maria, Guayaquil: Compare 10+ Sites & Save

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  2. Vacation Rentals
  3.  Ecuador

  4.  Guayas
  5.  Guayaquil
  6.  Santa Maria

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537 Best Vacation Rentals in Santa Maria (Starting from $25)

Cesar's House Guayaquil Home Rental
Cesar's House Guayaquil Home Rental
Villa
Santa Maria, Guayaquil, Guayas, Ecuador
2.1k from Santa Maria center

Balcony/Terrace, Laundry, Internet, Parking, Air Conditioner, Child Friendly

4 Bedrooms12 Guests
10.0

Exceptional

2 reviews

$150
Average price / night
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AS AT HOME THE BEST CHOICE
AS AT HOME THE BEST CHOICE
House
Guayaquil, 090112, Ecuador
1.0k from Santa Maria center

AC, Fitness Equipment, Free Parking, Kitchen, Laundry, Living Area, Microwave, No Smoking, Outdoor Space

6 Bedrooms10 Guests
10.0

Exceptional

1 reviews

$123
Average price / night
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2 room department (5 people). Private exclusive area in Guayaquil
2 room department (5 people). Private exclusive area in Guayaquil
Apartment
Guayaquil, Ecuador
2.2k from Santa Maria center

Apartments, Cheap, Accommodations, Pools, Parking, Pet-friendly, Lodgings, Vacation rentals, Jacuzzis

2 Bedrooms5 Guests
9.1

Superb

43 reviews

$56
Average price / night
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Habitación Privada en Los Ceibos - Garden View
Habitación Privada en Los Ceibos - Garden View
Villa
Guayaquil, 090910, Ecuador
1.7k from Santa Maria center

AC, Dryer, Free Parking, Internet, Kitchen, Laundry, Living Area, Microwave, TV

1 Bedroom3 Guests
New to Booking
$25
Average price / night
Check Availability
Acogedor y moderno loft con vista a la ciudad
Acogedor y moderno loft con vista a la ciudad
Apartment
Guayaquil, Ecuador
2.2k from Santa Maria center

Parking, Wheelchair Accessible, Air Conditioner, Child Friendly, Internet, Balcony/Terrace

1 Bedroom3 Guests
10.0

Exceptional

3 reviews

$54
Average price / night
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Private apartment quiet neighborhood GYE
Private apartment quiet neighborhood GYE
Apartment
Guayaquil, 0909507, Ecuador
2.5k from Santa Maria center

AC, Internet, Kitchen, Laundry, Microwave, No Smoking, TV, Washer

1 Bedroom3 Guests
New to Booking
$37
Average price / night
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Luxury Suite
Luxury Suite
Apartment
Guayaquil, Ecuador
2.2k from Santa Maria center

Balcony/Terrace, Parking, Smoking, Air Conditioner, Wheelchair Accessible, Internet, Child Friendly

2 Bedrooms5 Guests
1.0

Review score

1 reviews

$54
Average price / night
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Happy Villa With Pool in Guayaquil
Happy Villa With Pool in Guayaquil
Villa
Guayaquil, 090150, Ecuador
2.6k from Santa Maria center

AC, Dryer, Internet, Kitchen, Laundry, Living Area, Microwave, No Smoking, Pool

5 Bedrooms18 Guests
New to Booking
$239
Average price / night
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Cómodo dpto full equipo 2 hab, seguridad y parqueo privado
Cómodo dpto full equipo 2 hab, seguridad y parqueo privado
Apartment
Guayaquil, Ecuador
2.2k from Santa Maria center

Apartments, Cheap, Accommodations, Pools, Parking, Pet-friendly, Lodgings, Vacation rentals, Jacuzzis

2 Bedrooms6 Guests
9.2

Superb

45 reviews

$56
Average price / night
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SUITE EN GUAYAQUIL ECUADOR
SUITE EN GUAYAQUIL ECUADOR
Apartment
GUAYAQUIL, 090105, Ecuador
2.8k from Santa Maria center

AC, Dryer, Extra Bed, Fitness Equipment, Internet, Kitchen, Laundry, Microwave, No Smoking

1 Bedroom3 Guests
New to Booking
$110
Average price / night
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Departamento completo, facso
Departamento completo, facso
Apartment
Cuatro Hermanas, Ecuador
2.4k from Santa Maria center

Apartments, Cheap, Accommodations, Parking, Pet-friendly, Lodgings, Places to stay, Family, Self-catering

3 Bedrooms6 Guests
10.0

Exceptional

3 reviews

$39
Average price / night
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APARTAMENTO ENTERO NORTE DE GYE (ALL AMENITIES)
APARTAMENTO ENTERO NORTE DE GYE (ALL AMENITIES)
Apartment
guayaquil, 593, Ecuador
3.2k from Santa Maria center

AC, Internet, Microwave, TV

2 Bedrooms4 Guests
New to Booking
$65
Average price / night
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Con generador Suite elegante piscina gym en el norte Gye
Con generador Suite elegante piscina gym en el norte Gye
Apartment
Guayaquil, Ecuador
2.5k from Santa Maria center

Apartments, Cheap, Accommodations, Pools, Parking, Lodgings, Vacation rentals, Places to stay, Self-catering

1 Bedroom2 Guests
9.2

Superb

39 reviews

$39
Average price / night
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Ceibos Pearl Suite
Ceibos Pearl Suite
House
Guayaquil, 090904, Ecuador
3.2k from Santa Maria center

AC, Internet, Kitchen, Laundry, Microwave, No Smoking, Patio, TV, Washer

1 Bedroom1 Guest
New to Booking
$44
Average price / night
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SkyLuxe
SkyLuxe
Apartment
Guayaquil, Ecuador
2.5k from Santa Maria center

Air Conditioner, Internet, Parking, Pool, Child Friendly

2 Bedrooms4 Guests
New to Booking
$54
Average price / night
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Hermoso Apartamento en Guayaquil Casa Magda1
Hermoso Apartamento en Guayaquil Casa Magda1
Apartment
Guayaquil, 090507, Ecuador
3.3k from Santa Maria center

AC, Extra Bed, Internet, No Smoking

1 Bedroom4 Guests
New to Booking
$58
Average price / night
Check Availability
City suite vista a la ciudad
City suite vista a la ciudad
Apartment
Guayaquil, Ecuador
2.5k from Santa Maria center

Wheelchair Accessible, Parking, Private Pool, Pool, Internet, Pet Friendly, Air Conditioner

1 Bedroom3 Guests
9.5

Superb

2 reviews

$49
Average price / night
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Estamos cerca al Terminal Terrestre , Aeropuerto, Mall del Sol y demas lugares
Estamos cerca al Terminal Terrestre , Aeropuerto, Mall del Sol y demas lugares
Apartment
Guayaquil, 593, Ecuador
3.4k from Santa Maria center

AC, Internet, No Smoking

1 Bedroom4 Guests
New to Booking
$120
Average price / night
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GOLD SUITE CON VISTA A CIUDAD/PISCINA/GYM/PARQUEO
GOLD SUITE CON VISTA A CIUDAD/PISCINA/GYM/PARQUEO
Apartment
Guayaquil, Ecuador
2.5k from Santa Maria center

Parking, Security/Safety, Accessibility, Pool, Internet, Air Conditioner

1 Bedroom2 Guests
10.0

Exceptional

2 reviews

$62
Average price / night
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114 - Prague Apts 3 pax Consulate USA Parking
114 - Prague Apts 3 pax Consulate USA Parking
Apartment
Guayaquil, 090511, Ecuador
3.8k from Santa Maria center

AC, No Smoking

1 Bedroom3 Guests
New to Booking
$68
Average price / night
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Habitación - Guayaquil - Urdenor 2 - cerca de Urdesa
Habitación - Guayaquil - Urdenor 2 - cerca de Urdesa
Apartment
Ecuador
2.5k from Santa Maria center

Apartments, Cheap, Accommodations, Parking, Lodgings, Places to stay, Family

1 Bedroom2 Guests
9.0

Fabulous

8 reviews

$27
Average price / night
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110-Praga Apts 3 people close to the US consulate
110-Praga Apts 3 people close to the US consulate
Apartment
Guayaquil, 090511, Ecuador
3.8k from Santa Maria center

Laundry, No Smoking, Washer

1 Bedroom3 Guests
New to Booking
$94
Average price / night
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Modern and beautiful 3BD Industrial Loft in Lomas
Modern and beautiful 3BD Industrial Loft in Lomas
Apartment
Guayaquil, 090511, Ecuador
3.8k from Santa Maria center

AC, Balcony, Dryer, Free Parking, Heater, Internet, Kitchen, Microwave, No Smoking

3 Bedrooms7 Guests
New to Booking
$104
Average price / night
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Estancia del Viajero, Family Apartament in Guayaquil, next to the airport
Estancia del Viajero, Family Apartament in Guayaquil, next to the airport
Apartment
Guayaquil, 090607, Ecuador
3.8k from Santa Maria center

AC, Barbecue, Dryer, Free Parking, Kitchen, Laundry, Living Area, Microwave, No Smoking

2 Bedrooms4 Guests
New to Booking
$69
Average price / night
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Comfortable suite close to shopping centers, restaurants, linear park.
Comfortable suite close to shopping centers, restaurants, linear park.
Apartment
Guayaquil, 090512, Ecuador
3.8k from Santa Maria center

AC, No Smoking, TV

1 Bedroom2 Guests
New to Booking
$59
Average price / night
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Departamentos en la Garzota
Departamentos en la Garzota
Apartment
4to Callejon 15E NE, Guayaquil, 090501, Ecuador
3.9k from Santa Maria center

AC, Grocery, Internet, Kitchen, Laundry, Microwave, No Smoking

1 Bedroom4 Guests
New to Booking
$30
Average price / night
Check Availability
Elegant LOFT in Guayaquil w/2 Beds Near to Airport
Elegant LOFT in Guayaquil w/2 Beds Near to Airport
Apartment
Guayaquil, 090511, Ecuador
3.9k from Santa Maria center

AC, Internet, No Smoking

1 Bedroom3 Guests
New to Booking
$83
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in Santa Maria.

Stay Near Santa Maria's Top Attractions

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Santa Maria Vacation Rentals on the Map

Frequently Asked Questions

You can explore 537 verified vacation rentals in Santa Maria. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in Santa Maria vary depending on the season, property size, and location. Rates typically start from around $25 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in Santa Maria include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in Santa Maria welcome pets. Currently, 33 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in Santa Maria often include amenities such as Internet, Laundry, and Bedding/Linens. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.