Vacation Rentals in Panama City, Panama: Compare 10+ Sites & Save

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1135 Best Vacation Rentals in Panama City (Starting from $27)

Habitaciones privadas en un departamento encantador
Habitaciones privadas en un departamento encantador
House
Panama City, Panama
0.2k from Panama City center

Tv, Internet, Balcony/Terrace, Guest Services, Kitchen, Accessibility, Air Conditioner

7 Bedrooms10 Guests
9.2

Superb

185 reviews

$27
Average price / night
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Lovely Studio at the Heart of the City
Lovely Studio at the Heart of the City
Apartment
panana City, Panama
0.1k from Panama City center

AC, Heater, Internet, Laundry, No Smoking

1 Bedroom2 Guests
New to Booking
$49
Average price / night
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Central Modern Apartment AC/Pool/Wifi
Central Modern Apartment AC/Pool/Wifi
Apartment
Panama City, Panama
0.2k from Panama City center

Wheelchair Accessible, Kitchen, Pool, Balcony/Terrace, Parking, Internet, Air Conditioner

1 Bedroom2 Guests
New to Booking
$72
Average price / night
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Exclusive and luxury 1BR with balcony in Yoo Panama
Exclusive and luxury 1BR with balcony in Yoo Panama
Apartment
Panamá, 807, Panama
0.2k from Panama City center

AC, Balcony, Dryer, Elevator, Fitness Equipment, Heater, Internet, Kitchen, Laundry

1 Bedroom2 Guests
New to Booking
$246
Average price / night
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Hermoso Apartamento ven de trabajo o turismo te va a encantar
Hermoso Apartamento ven de trabajo o turismo te va a encantar
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Cheap, Accommodations, Pools, Parking, Pet-friendly, Lodgings, Places to stay, Family

2 Bedrooms5 Guests
9.8

Exceptional

15 reviews

$127
Average price / night
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Céntrico apartamento en Panama cerca al Metro
Céntrico apartamento en Panama cerca al Metro
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Cheap, Accommodations, Parking, Pet-friendly, Lodgings, Places to stay, Family, Self-catering

1 Bedroom2 Guests
9.2

Superb

18 reviews

$89
Average price / night
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THE URBAN LOFT 2 - LA RÉSIDENCE PANAMÁ
THE URBAN LOFT 2 - LA RÉSIDENCE PANAMÁ
Apartment
Panamá, Panama
0.2k from Panama City center

AC, Dryer, Fitness Equipment, Heater, Internet, Laundry, No Smoking, Washer

2 Bedrooms4 Guests
New to Booking
$571
Average price / night
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Apartamento con calor de hogar 23L
Apartamento con calor de hogar 23L
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Accommodations, Pools, Parking, Lodgings, Places to stay

1 Bedroom2 Guests
4.0

Review score

1 reviews

$103
Average price / night
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THE CITY SUITE -  LA RÉSIDENCE PANAMÁ
THE CITY SUITE - LA RÉSIDENCE PANAMÁ
Apartment
Panamá, Panama
0.2k from Panama City center

AC, Dryer, Fitness Equipment, Heater, Internet, Laundry, No Smoking, Washer

1 Bedroom3 Guests
New to Booking
$571
Average price / night
Check Availability
Apartamento con calor de hogar
Apartamento con calor de hogar
Apartment
Panama City, Panama
0.3k from Panama City center

Pool, Internet, Security/Safety, Air Conditioner, Parking, Balcony/Terrace, Child Friendly

1 Bedroom2 Guests
New to Booking
$95
Average price / night
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Studio Coliving Suite
Studio Coliving Suite
Apartment
Panama, 0801, Panama
0.2k from Panama City center

AC, Internet, No Smoking, Pool, TV

1 Bedroom2 Guests
New to Booking
$115
Average price / night
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Espectacular aparta estudio
Espectacular aparta estudio
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Accommodations, Pools, Parking, Lodgings, Places to stay, Family, Self-catering

2 Bedrooms4 Guests
7.0

Good

1 reviews

$101
Average price / night
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Beutiful Modern Apartment, High Speed Internet, Best Location
Beutiful Modern Apartment, High Speed Internet, Best Location
Apartment
Panamá, Panama
0.2k from Panama City center

AC, Balcony, Elevator, Fitness Equipment, Free Parking, Internet, Kitchen, Laundry, Microwave

1 Bedroom90 Guests
9.8

Exceptional

13 reviews

$132
Average price / night
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Apartment Slice of Gray
Apartment Slice of Gray
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Cheap, Accommodations, Pools, Parking, Lodgings, Places to stay, Family, Self-catering

1 Bedroom2 Guests
9.5

Superb

4 reviews

$139
Average price / night
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w *| Positioned 1BR w/ Beautiful View in Calle 50
w *| Positioned 1BR w/ Beautiful View in Calle 50
Apartment
Panamá, 823, Panama
0.3k from Panama City center

AC, Balcony, Dryer, Elevator, Extra Bed, Fitness Equipment, Free Parking, Internet, Kitchen

1 Bedroom4 Guests
8.0

Good

2 reviews

$108
Average price / night
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1BR Amazing sea view in Calle 50
1BR Amazing sea view in Calle 50
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Accommodations, Parking, Lodgings, Places to stay

1 Bedroom2 Guests
New to Booking
$90
Average price / night
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Beautiful Apartment come for work or tourism you will love it
Beautiful Apartment come for work or tourism you will love it
Apartment
PANAMA, 00007096, Panama
0.3k from Panama City center

AC, Balcony, Dryer, Extra Bed, Free Parking, Internet, Kitchen, Laundry, Microwave

2 Bedrooms5 Guests
New to Booking
$131
Average price / night
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The Gray by Wynwood House
The Gray by Wynwood House
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Accommodations, Pools, Lodgings, Places to stay, Self-catering

9 Bedrooms27 Guests
7.4

Good

15 reviews

$125
Average price / night
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Border Village (pool & bbq) by: Abitare Rentals
Border Village (pool & bbq) by: Abitare Rentals
Apartment
Panamá, ----, Panama
0.3k from Panama City center

AC, Dryer, Internet, Laundry, No Smoking, Washer

2 Bedrooms25 Guests
New to Booking
$1096
Average price / night
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Apartment with city views in Financial District
Apartment with city views in Financial District
Apartment
Panama City, Panama
0.3k from Panama City center

Apartments, Accommodations, Pools, Parking, Lodgings, Places to stay

1 Bedroom4 Guests
New to Booking
$108
Average price / night
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w *| Cautious 1BR w/ Great View in Calle 50
w *| Cautious 1BR w/ Great View in Calle 50
Apartment
Panamá, 823, Panama
0.3k from Panama City center

AC, Dryer, Elevator, Fitness Equipment, Free Parking, Internet, Kitchen, Laundry, Living Area

1 Bedroom2 Guests
10.0

Exceptional

1 reviews

$129
Average price / night
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w *| Carefree 1BR w/ Great View in Calle 50
w *| Carefree 1BR w/ Great View in Calle 50
Apartment
Panamá, 0823, Panama
0.3k from Panama City center

AC, Balcony, Dryer, Elevator, Fitness Equipment, Free Parking, Internet, Kitchen, Laundry

1 Bedroom4 Guests
New to Booking
$152
Average price / night
Check Availability
THE CORNER SUITE - LA RÉSIDENCE PANAMÁ
THE CORNER SUITE - LA RÉSIDENCE PANAMÁ
Apartment
Panamá, Panama
0.3k from Panama City center

AC, Dryer, Fitness Equipment, Heater, Internet, Laundry, No Smoking, Washer

1 Bedroom2 Guests
New to Booking
$571
Average price / night
Check Availability
THE URBAN LOFT 3 - LA RÉSIDENCE PANAMÁ
THE URBAN LOFT 3 - LA RÉSIDENCE PANAMÁ
Apartment
Panamá, Panama
0.3k from Panama City center

AC, Dryer, Fitness Equipment, Heater, Internet, Laundry, No Smoking, Washer

2 Bedrooms5 Guests
New to Booking
$571
Average price / night
Check Availability
Lovely studio apartment in the heart of the city
Lovely studio apartment in the heart of the city
House
panana city, Panama
0.3k from Panama City center

AC, Heater, Internet, No Smoking

1 Bedroom2 Guests
New to Booking
$55
Average price / night
Check Availability
w *| Sophisticated 1BR w/ High-Rise View in Calle 50
w *| Sophisticated 1BR w/ High-Rise View in Calle 50
Apartment
Panamá, Panama
0.3k from Panama City center

AC, Balcony, Dryer, Elevator, Fitness Equipment, Free Parking, Internet, Kitchen, Laundry

1 Bedroom3 Guests
New to Booking
$102
Average price / night
Check Availability
w* | Custom 1BR w/ Beautiful View in Calle 50
w* | Custom 1BR w/ Beautiful View in Calle 50
Apartment
Panamá, Panama
0.3k from Panama City center

AC, Balcony, Dryer, Elevator, Fitness Equipment, Free Parking, Internet, Kitchen, Laundry

1 Bedroom4 Guests
New to Booking
$138
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in Panama City.

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Panama City Vacation Rentals on the Map

Frequently Asked Questions

You can explore 1135 verified vacation rentals in Panama City. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in Panama City vary depending on the season, property size, and location. Rates typically start from around $27 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in Panama City include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in Panama City welcome pets. Currently, 23 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in Panama City often include amenities such as Wellness Facilities, Balcony/Terrace, and Laundry. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.