Vacation Rentals in Panacea, FL: Compare 10+ Sites & Save

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209 Best Vacation Rentals in Panacea (Starting from $144)

Private Beach and Dock Waterfront Panacea Retreat!
Private Beach and Dock Waterfront Panacea Retreat!
House
Panacea, FL, USA
2.1k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals, Beach, Places to stay

3 Bedrooms7 Guests
New to Booking
$261
Average price / night
Check Availability
Angler's Rest- Hooked on Relaxation
Angler's Rest- Hooked on Relaxation
House
Panacea, FL, 32346, United States
1.7k from Panacea center

AC, Balcony, Dryer, Free Parking, Internet, Kitchen, Living Area, Microwave, No Smoking

3 Bedrooms8 Guests
New to Booking
$264
Average price / night
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romantic getaway bayside
romantic getaway bayside
Apartment
Panacea, FL, USA
2.1k from Panacea center

Apartments, Cheap, Accommodations, Pools, Parking, Lodgings, Places to stay, Self-catering, Condos

1 Bedroom2 Guests
9.2

Superb

15 reviews

$144
Average price / night
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Tide Creek Bungalow — Where the Bay Meets Comfort
Tide Creek Bungalow — Where the Bay Meets Comfort
House
Panacea, FL, 32346, United States
1.9k from Panacea center

AC, Balcony, Dryer, Free Parking, Heater, Internet, Kitchen, Living Area, Microwave

1 Bedroom4 Guests
New to Booking
$163
Average price / night
Check Availability
2 Mi to Mashes Sands Beach Quiet Home with Dock!
2 Mi to Mashes Sands Beach Quiet Home with Dock!
House
Panacea, FL, USA
2.2k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

3 Bedrooms6 Guests
8.0

Good

2 reviews

$412
Average price / night
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Private Beach & Dock - Quiet Waterfront Retreat on Ochlockonee Bay
Private Beach & Dock - Quiet Waterfront Retreat on Ochlockonee Bay
House
Panacea, FL, 32346, United States
2.0k from Panacea center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, No Smoking, Outdoor Space

3 Bedrooms7 Guests
10.0

Exceptional

1 reviews

$418
Average price / night
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Shoreline Serenity- The Golden Goat On The Bay
Shoreline Serenity- The Golden Goat On The Bay
House
Panacea, FL, USA
2.3k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

2 Bedrooms4 Guests
New to Booking
$234
Average price / night
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Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis
Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis
House
Alligator Point, FL, 32346, United States
2.0k from Panacea center

AC, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Hot Tub, Internet

3 Bedrooms6 Guests
10.0

Exceptional

4 reviews

$322
Average price / night
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Perfect Summer Vacation/Waterfront Property/Bay Views/Ocean Views/Boat Dock/Kayak/Dog Friendly!
Perfect Summer Vacation/Waterfront Property/Bay Views/Ocean Views/Boat Dock/Kayak/Dog Friendly!
House
Panacea, FL, USA
2.7k from Panacea center

Accommodations, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Beach, Places to stay, Family

3 Bedrooms6 Guests
New to Booking
$526
Average price / night
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Hideaway Beach Cottage on waterfront with amazing views.
Hideaway Beach Cottage on waterfront with amazing views.
Cottage
Panacea, FL, 32346, United States
2.0k from Panacea center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry

2 Bedrooms6 Guests
10.0

Exceptional

65 reviews

$277
Average price / night
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Relax and Refresh Waterfront Cottage in Panacea
Relax and Refresh Waterfront Cottage in Panacea
House
Panacea, FL, USA
3.2k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

2 Bedrooms5 Guests
New to Booking
$243
Average price / night
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Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay
Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay
House
Panacea, FL, 32346, United States
2.1k from Panacea center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

2 Bedrooms6 Guests
9.6

Exceptional

9 reviews

$184
Average price / night
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Waterfront Ochlockonee Bay Cottage with Views!
Waterfront Ochlockonee Bay Cottage with Views!
House
Panacea, FL, USA
3.7k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals, Beach, Places to stay

2 Bedrooms8 Guests
8.4

Very Good

6 reviews

$208
Average price / night
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Bayfront Ochlocknee Bay/Ocean View/Boat Dock 1-bedroom home top floor  2nd floor
Bayfront Ochlocknee Bay/Ocean View/Boat Dock 1-bedroom home top floor 2nd floor
House
Panacea, FL, 32346, United States
2.1k from Panacea center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

1 Bedroom4 Guests
10.0

Exceptional

3 reviews

$194
Average price / night
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Waterfront Home Spectacular On-Site Fishing!
Waterfront Home Spectacular On-Site Fishing!
House
Panacea, FL, USA
3.8k from Panacea center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals, Places to stay

3 Bedrooms10 Guests
9.3

Superb

3 reviews

$524
Average price / night
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2 Mi to Mashes Sands Beach: Quiet Home w/ Dock!
2 Mi to Mashes Sands Beach: Quiet Home w/ Dock!
House
Panacea, FL, 32346, United States
2.2k from Panacea center

AC, Barbecue, Dryer, Extra Bed, Fireplace, Free Parking, Heater, Internet, Kitchen

3 Bedrooms6 Guests
9.4

Superb

8 reviews

$198
Average price / night
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Waterfront Panacea Vacation Rental with Dock!
Waterfront Panacea Vacation Rental with Dock!
House
Panacea, FL, USA
3.8k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals, Places to stay, Beach rentals

3 Bedrooms8 Guests
New to Booking
$206
Average price / night
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Cozy bayfront farmhouse!
Cozy bayfront farmhouse!
House
Panacea, FL, 32346, United States
2.3k from Panacea center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave

2 Bedrooms4 Guests
9.8

Exceptional

6 reviews

$276
Average price / night
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Pachs Crab Shack
Pachs Crab Shack
House
Panacea, FL, USA
3.9k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Beach, Jacuzzis, Places to stay

1 Bedroom6 Guests
New to Booking
$246
Average price / night
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 Cabin By the Bay A unique authentic log cabin by the beach with fenced yard
Cabin By the Bay A unique authentic log cabin by the beach with fenced yard
Cabin
Panacea, FL, 32346, United States
2.5k from Panacea center

AC, Barbecue, Dryer, Extra Bed, Fireplace, Free Parking, Heater, Internet, Kitchen

4 Bedrooms8 Guests
10.0

Exceptional

20 reviews

$285
Average price / night
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Sardegna- Pool Home On The Canal!
Sardegna- Pool Home On The Canal!
House
Sun N Sand Beaches, FL, USA
4.0k from Panacea center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

1 Bedroom6 Guests
New to Booking
$257
Average price / night
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Bayfront Property/ Ocean Views/ Boat Dock/ Kayak/Large Parking/ Dog Friendly
Bayfront Property/ Ocean Views/ Boat Dock/ Kayak/Large Parking/ Dog Friendly
House
Panacea, FL, 32346, United States
2.7k from Panacea center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms6 Guests
10.0

Exceptional

31 reviews

$310
Average price / night
Check Availability
Ochlockonee Bay 4 bedrooms, waterfront, pool, dock, fishing.
Ochlockonee Bay 4 bedrooms, waterfront, pool, dock, fishing.
House
Panacea, FL, 32346, United States
2.8k from Panacea center

AC, Barbecue, Dryer, Fireplace, Fitness Equipment, Free Parking, Heater, Internet, Kitchen

4 Bedrooms8 Guests
New to Booking
$538
Average price / night
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Bay Dreamin' the Forgotten Coast 4 BR/3 BA Waterfront Home on Ochlockonee Bay
Bay Dreamin' the Forgotten Coast 4 BR/3 BA Waterfront Home on Ochlockonee Bay
House
Panacea, FL, 32346, United States
2.8k from Panacea center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

4 Bedrooms12 Guests
9.2

Superb

47 reviews

$284
Average price / night
Check Availability
Relax with the whole family at this peaceful place to stay.
Relax with the whole family at this peaceful place to stay.
House
Panacea, FL, 32346, United States
2.8k from Panacea center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

4 Bedrooms11 Guests
8.6

Fabulous

8 reviews

$362
Average price / night
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Tiny Tides Waterfront Cottage
Tiny Tides Waterfront Cottage
House
Panacea, FL, 32346, United States
2.9k from Panacea center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

2 Bedrooms6 Guests
10.0

Exceptional

8 reviews

$279
Average price / night
Check Availability
Blue Zone – Your no-stress zone for sun-soaked fun
Blue Zone – Your no-stress zone for sun-soaked fun
House
panacea, FL, 32346, United States
2.9k from Panacea center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Living Area, Microwave, No Smoking

3 Bedrooms6 Guests
9.6

Exceptional

4 reviews

$331
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in Panacea.

Stay Near Panacea's Top Attractions

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Panacea Vacation Rentals on the Map

Frequently Asked Questions

You can explore 209 verified vacation rentals in Panacea. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in Panacea vary depending on the season, property size, and location. Rates typically start from around $144 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in Panacea include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in Panacea welcome pets. Currently, 35 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in Panacea often include amenities such as Fireplace/Heating, Internet, and View. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.