Vacation Rentals in Mayo Clinic Health System, MN: Compare 10+ Sites & Save

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  4.  Minnesota
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  6.  Mayo Clinic Health System

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66 Best Vacation Rentals in Mayo Clinic Health System (Starting from $130)

2nd Floor, 2 Bedroom Condo, Sleeps 6
2nd Floor, 2 Bedroom Condo, Sleeps 6
House
Lake City, MN, USA
0.4k from Mayo Clinic Health System center

Cheap, Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings

2 Bedrooms6 Guests
9.0

Fabulous

4 reviews

$206
Average price / night
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Modern style, 1 block from Lake Pepin
Modern style, 1 block from Lake Pepin
House
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Extra Bed, Free Parking, Heater, Internet, Kitchen, Living Area, Microwave, No Smoking

2 Bedrooms6 Guests
9.6

Exceptional

22 reviews

$197
Average price / night
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Seasonal Cabin, sleeps 6
Seasonal Cabin, sleeps 6
Apartment
Mayo Clinic Health System, Lake City, Minnesota, USA
0.4k from Mayo Clinic Health System center

Apartments, Accommodations, Pools, Parking, Lodgings, Vacation rentals, Places to stay

1 Bedroom4 Guests
New to Booking
$177
Average price / night
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Double Queen Room Sum
Double Queen Room Sum
Apartment
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Free Parking, Heater, Internet, No Smoking, Pool, TV

1 Bedroom4 Guests
10.0

Exceptional

1 reviews

$130
Average price / night
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3 Bedroom Condo with Lake Pepin views with access to shared outdoor pool
3 Bedroom Condo with Lake Pepin views with access to shared outdoor pool
House
Lake City, MN, USA
0.4k from Mayo Clinic Health System center

Cheap, Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings

3 Bedrooms6 Guests
7.0

Good

1 reviews

$227
Average price / night
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3 Bedroom House with Lake Pepin views with access to shared pool
3 Bedroom House with Lake Pepin views with access to shared pool
House
Lake City, MN, USA
0.4k from Mayo Clinic Health System center

Cheap, Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings

3 Bedrooms8 Guests
9.5

Superb

2 reviews

$247
Average price / night
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Single King Room w/ Sleeper Sofa (main level)
Single King Room w/ Sleeper Sofa (main level)
Apartment
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Free Parking, Heater, Internet, No Smoking, Pool, TV

1 Bedroom4 Guests
10.0

Exceptional

2 reviews

$130
Average price / night
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2 Bedroom Suite with kitchen
2 Bedroom Suite with kitchen
Apartment
Lake City, MN, USA
0.4k from Mayo Clinic Health System center

Apartments, Cheap, Accommodations, Parking, Pet-friendly, Lodgings, Vacation rentals, Places to stay, Family

3 Bedrooms6 Guests
8.7

Fabulous

3 reviews

$227
Average price / night
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2 Bedroom Suite with kitchenette (main level)
2 Bedroom Suite with kitchenette (main level)
Apartment
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

Extra Bed, Kitchen, No Smoking

3 Bedrooms6 Guests
8.8

Fabulous

3 reviews

$188
Average price / night
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Red Hibiscus House - 3 Blocks from Lake Pepin
Red Hibiscus House - 3 Blocks from Lake Pepin
House
MN, USA
1.6k from Mayo Clinic Health System center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay, Family

5 Bedrooms12 Guests
New to Booking
$428
Average price / night
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3 Bedroom home (sleeps 8)
3 Bedroom home (sleeps 8)
House
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Balcony, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

3 Bedrooms8 Guests
9.8

Exceptional

6 reviews

$348
Average price / night
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Jasmine Apartment - 3 Blocks from Lake Pepin
Jasmine Apartment - 3 Blocks from Lake Pepin
Apartment
MN, USA
1.6k from Mayo Clinic Health System center

Apartments, Accommodations, Parking, Lodgings, Places to stay, Family

2 Bedrooms6 Guests
New to Booking
$236
Average price / night
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Single Queen Room (main level)
Single Queen Room (main level)
Apartment
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Free Parking, Heater, Internet, No Smoking, Pool, TV

1 Bedroom2 Guests
4.0

Review score

1 reviews

$130
Average price / night
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Fire Lily Apartment - 3 Blocks from Lake Pepin
Fire Lily Apartment - 3 Blocks from Lake Pepin
Apartment
MN, USA
1.6k from Mayo Clinic Health System center

Apartments, Accommodations, Parking, Lodgings, Places to stay, Family

2 Bedrooms7 Guests
New to Booking
$245
Average price / night
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Poolside Double Queen Room (main level)
Poolside Double Queen Room (main level)
Apartment
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Free Parking, Heater, Internet, No Smoking, Pool, TV

1 Bedroom4 Guests
New to Booking
$163
Average price / night
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Blue Iris House - 5 Beds Walking Distance to Beach
Blue Iris House - 5 Beds Walking Distance to Beach
House
MN, USA
1.7k from Mayo Clinic Health System center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay, Family

5 Bedrooms12 Guests
New to Booking
$383
Average price / night
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Snowdrop Apartment - Just 10 Minutes to the Beach!
Snowdrop Apartment - Just 10 Minutes to the Beach!
Apartment
MN, USA
1.7k from Mayo Clinic Health System center

Apartments, Accommodations, Parking, Lodgings, Places to stay, Family

3 Bedrooms7 Guests
New to Booking
$285
Average price / night
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Marigold Apartment - Cute Loft 5 Minutes to Marina
Marigold Apartment - Cute Loft 5 Minutes to Marina
Apartment
MN, USA
1.7k from Mayo Clinic Health System center

Apartments, Accommodations, Parking, Lodgings, Places to stay, Family, Self-catering

2 Bedrooms5 Guests
9.0

Fabulous

1 reviews

$202
Average price / night
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1 Block to Lake City Marina Condo with Rooftop Deck
1 Block to Lake City Marina Condo with Rooftop Deck
Apartment
Lake City, MN, USA
2.0k from Mayo Clinic Health System center

Apartments, Accommodations, Parking, Spa, Lodgings, Places to stay, Condos

2 Bedrooms5 Guests
New to Booking
$378
Average price / night
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Single King Room (Upper Level)
Single King Room (Upper Level)
Apartment
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Free Parking, Heater, Internet, No Smoking, Pool, TV

1 Bedroom2 Guests
9.0

Fabulous

2 reviews

$130
Average price / night
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Main Floor Cabin (sleeps 4)
Main Floor Cabin (sleeps 4)
Apartment
Lake City, MN, 55041, United States
0.4k from Mayo Clinic Health System center

AC, Barbecue, Free Parking, Heater, Internet, Kitchen, No Smoking, Pool, TV

1 Bedroom4 Guests
New to Booking
$195
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in Mayo Clinic Health System.

Mayo Clinic Health System Vacation Rentals on the Map

Frequently Asked Questions

You can explore 66 verified vacation rentals in Mayo Clinic Health System. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in Mayo Clinic Health System vary depending on the season, property size, and location. Rates typically start from around $130 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in Mayo Clinic Health System include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in Mayo Clinic Health System welcome pets. Currently, 35 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in Mayo Clinic Health System often include amenities such as Fireplace/Heating, Child Friendly, and Internet. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.