Vacation Rentals in Downtown, MO: Compare 10+ Sites & Save

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  6.  Downtown

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630 Best Vacation Rentals in Downtown (Starting from $49)

St Louis Perfect Getaway in a Central Location
St Louis Perfect Getaway in a Central Location
Apartment
Downtown, St. Louis, Missouri, USA
2.6k from Downtown center

Parking, Internet, Air Conditioner, Child Friendly

2 Bedrooms4 Guests
New to Booking
$68
Average price / night
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King Bed, Comfy Environment, Cozy Space, Corporate Luxury
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Apartment
Clayton, MO, 63105, United States
0.4k from Downtown center

AC, Arcade, Barbecue, Dryer, Elevator, Extra Bed, Fitness Equipment, Free Parking, Heater

2 Bedrooms2 Guests
9.4

Superb

3 reviews

$294
Average price / night
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Discover St Louis in a Cozy APT with Pool and Gym
Discover St Louis in a Cozy APT with Pool and Gym
Apartment
Downtown, St. Louis, Missouri, USA
2.6k from Downtown center

Parking, Internet, Air Conditioner, Child Friendly

2 Bedrooms4 Guests
New to Booking
$68
Average price / night
Check Availability
Charming 2-bedroom house within walking distance to Washu and Downtown Clayton
Charming 2-bedroom house within walking distance to Washu and Downtown Clayton
House
St. Louis, MO, 63105, United States
1.5k from Downtown center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Laundry, Living Area

2 Bedrooms8 Guests
New to Booking
$195
Average price / night
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Spacious Retreat with Serene Garden Sleeps up to Eleven
Spacious Retreat with Serene Garden Sleeps up to Eleven
House
Olivette, MO, USA
3.1k from Downtown center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay, Family

5 Bedrooms11 Guests
New to Booking
$309
Average price / night
Check Availability
LOCATION, LOCATION, LOCATION!!! University City \"home-away-from-home.\"
LOCATION, LOCATION, LOCATION!!! University City \"home-away-from-home.\"
House
University City, MO, 63130, United States
1.6k from Downtown center

AC, Dryer, Extra Bed, Fireplace, Heater, Kitchen, Laundry, No Smoking, Patio

2 Bedrooms4 Guests
10.0

Exceptional

2 reviews

$221
Average price / night
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Cute Neighborhood Rainbow Apt
Cute Neighborhood Rainbow Apt
Apartment
Saint Louis, MO, USA
3.4k from Downtown center

Apartments, Accommodations, Parking, Pet-friendly, Lodgings, Places to stay

8 Bedrooms26 Guests
New to Booking
$138
Average price / night
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EPIC PICKLE BALL GUEST RETREAT
EPIC PICKLE BALL GUEST RETREAT
House
St. Louis, MO, 63124, United States
1.7k from Downtown center

AC, Dryer, Heater, Internet, Laundry, No Smoking, Washer

1 Bedroom2 Guests
10.0

Exceptional

5 reviews

$224
Average price / night
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The Urban Nest – Your St. Louis City Retreat!
The Urban Nest – Your St. Louis City Retreat!
House
Saint Louis, MO, USA
3.8k from Downtown center

Parking, Air Conditioner, Internet, Fireplace/Heating, Security/Safety, Pet Friendly

2 Bedrooms4 Guests
New to Booking
$208
Average price / night
Check Availability
Loop Luxe in University City
Loop Luxe in University City
Villa
University City, MO, 63130, United States
1.7k from Downtown center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Laundry, Microwave

2 Bedrooms4 Guests
New to Booking
$89
Average price / night
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(55.1S) Experience a True STL Visit!
(55.1S) Experience a True STL Visit!
Apartment
Benton, MO, USA
3.8k from Downtown center

Apartments, Accommodations, Parking, Lodgings, Vacation rentals, Places to stay, Self-catering

2 Bedrooms4 Guests
7.1

Good

9 reviews

$108
Average price / night
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Charming 2-bedroom apartment with AC in University City
Charming 2-bedroom apartment with AC in University City
Apartment
University City, MO, 63130, United States
1.8k from Downtown center

AC, Dryer, Heater, Internet, Laundry, No Smoking, Washer

2 Bedrooms4 Guests
New to Booking
$213
Average price / night
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(53.1N) Walk to Forest Park in Comfort!
(53.1N) Walk to Forest Park in Comfort!
Apartment
Benton, MO, USA
3.8k from Downtown center

Apartments, Cheap, Accommodations, Parking, Lodgings, Vacation rentals, Places to stay, Self-catering

1 Bedroom2 Guests
7.7

Good

11 reviews

$63
Average price / night
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Modern Duplex, Quiet, Safe, home office in desirable U City
Modern Duplex, Quiet, Safe, home office in desirable U City
Apartment
University City, MO, 63130, United States
1.9k from Downtown center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

2 Bedrooms4 Guests
10.0

Exceptional

1 reviews

$102
Average price / night
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(49.1E) Garden style studio @ Forest Park & City!
(49.1E) Garden style studio @ Forest Park & City!
Apartment
Benton, MO, USA
3.8k from Downtown center

Apartments, Cheap, Accommodations, Parking, Lodgings, Vacation rentals, Places to stay, Self-catering

1 Bedroom2 Guests
7.1

Good

39 reviews

$66
Average price / night
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Tranquil three bedroom SpaHome in central St. Louis.
Tranquil three bedroom SpaHome in central St. Louis.
House
St. Louis, MO, 63130, United States
1.9k from Downtown center

AC, Barbecue, Crib, Dryer, Fireplace, Fitness Equipment, Free Parking, Heater, Internet

3 Bedrooms6 Guests
10.0

Exceptional

3 reviews

$293
Average price / night
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(53.1S) Forest Park, The Zoo, and much more
(53.1S) Forest Park, The Zoo, and much more
Apartment
Benton, MO, USA
3.8k from Downtown center

Apartments, Accommodations, Parking, Lodgings, Vacation rentals, Places to stay

2 Bedrooms4 Guests
6.3

Good

21 reviews

$49
Average price / night
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The Delmar Darling - Walk to Loop + Near Wash U
The Delmar Darling - Walk to Loop + Near Wash U
House
St. Louis, MO, 63130, United States
1.9k from Downtown center

AC, Dryer, Internet, Laundry, No Smoking, Washer

4 Bedrooms10 Guests
New to Booking
$344
Average price / night
Check Availability
(49.1W) Beautiful Getaway in Saint Louis
(49.1W) Beautiful Getaway in Saint Louis
Apartment
Benton, MO, USA
3.8k from Downtown center

Apartments, Accommodations, Parking, Lodgings, Vacation rentals, Places to stay, Self-catering

1 Bedroom2 Guests
6.7

Good

16 reviews

$94
Average price / night
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Spacious Aparment in the center of St. Louis.
Spacious Aparment in the center of St. Louis.
Apartment
Richmond Heights, MO, 63117, United States
2.1k from Downtown center

AC, Dryer, Heater, Laundry, Microwave, No Smoking, TV

1 Bedroom2 Guests
10.0

Exceptional

1 reviews

$69
Average price / night
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St Louis Family Friendly Gem in Dogtown
St Louis Family Friendly Gem in Dogtown
House
Saint Louis, MO, USA
4.1k from Downtown center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay, Family

1 Bedroom7 Guests
New to Booking
$280
Average price / night
Check Availability
Delightful Cottage by Clayton
Delightful Cottage by Clayton
Cottage
University City, MO, 63130, United States
2.2k from Downtown center

AC, Dryer, Heater, Internet, Laundry, No Smoking, Washer

2 Bedrooms4 Guests
10.0

Exceptional

2 reviews

$165
Average price / night
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Cozy 2BR Home in Delmar Loop
Cozy 2BR Home in Delmar Loop
House
University City, MO, 63130, United States
2.5k from Downtown center

AC, Dryer, Heater, Internet, Laundry, No Smoking, Washer

2 Bedrooms4 Guests
10.0

Exceptional

3 reviews

$176
Average price / night
Check Availability
\"The Loop\" 10min walk: Restaurants + Bars, Wash U
\"The Loop\" 10min walk: Restaurants + Bars, Wash U
House
University City, MO, 63130, United States
2.6k from Downtown center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

2 Bedrooms4 Guests
8.0

Good

1 reviews

$102
Average price / night
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Smoke Free!!The Rock House Bnb, StL. Centrally Located + Park. 8 person Max!
Smoke Free!!The Rock House Bnb, StL. Centrally Located + Park. 8 person Max!
House
University City, MO, 63130, United States
2.7k from Downtown center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry

2 Bedrooms8 Guests
9.6

Exceptional

11 reviews

$278
Average price / night
Check Availability
Cozy, quiet,clean home settings
Cozy, quiet,clean home settings
House
St. Louis, MO, 63132, United States
2.9k from Downtown center

Extra Bed, No Smoking

2 Bedrooms6 Guests
New to Booking
$148
Average price / night
Check Availability
Cute Apt Near Loop - WashU - BJC
Cute Apt Near Loop - WashU - BJC
Apartment
University City, MO, 63130, United States
2.9k from Downtown center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

3 Bedrooms5 Guests
9.6

Exceptional

5 reviews

$158
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in Downtown.

Stay Near Downtown's Top Attractions

VacationByOwnerRentals can help you find hotels, resorts, and rentals near many of 's top attractions, neighborhoods, and points of interest.

Downtown Vacation Rentals on the Map

Frequently Asked Questions

You can explore 630 verified vacation rentals in Downtown. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in Downtown vary depending on the season, property size, and location. Rates typically start from around $49 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in Downtown include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in Downtown welcome pets. Currently, 30 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in Downtown often include amenities such as Fireplace/Heating, Laundry, and Internet. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.