Vacation Rentals in Depew, NY: Compare 10+ Sites & Save

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153 Best Vacation Rentals in Depew (Starting from $129)

Sharuns Vacation House
Sharuns Vacation House
Apartment
Depew, NY, USA
1.7k from Depew center

Parking, Internet, Security/Safety, Air Conditioner, Child Friendly

1 Bedroom6 Guests
New to Booking
$198
Average price / night
Check Availability
Beautiful 3 bedroom house close to airport, downtown, stadium, and more!
Beautiful 3 bedroom house close to airport, downtown, stadium, and more!
House
Depew, NY, 14043, United States
0.6k from Depew center

AC, Dryer, Fireplace, Fitness Equipment, Free Parking, Heater, Internet, Kitchen, Laundry

3 Bedrooms8 Guests
New to Booking
$289
Average price / night
Check Availability
Cozy Duplex Near BUF International Airport
Cozy Duplex Near BUF International Airport
Apartment
Cheektowaga, NY, USA
2.7k from Depew center

Apartments, Cheap, Accommodations, Parking, Pet-friendly, Lodgings, Places to stay, Family, Self-catering

2 Bedrooms5 Guests
9.5

Superb

2 reviews

$129
Average price / night
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Quiet suburban home 10 minutes from airport/25 min from Niagara Falls
Quiet suburban home 10 minutes from airport/25 min from Niagara Falls
Apartment
Depew, NY, 14043, United States
0.6k from Depew center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

3 Bedrooms6 Guests
10.0

Exceptional

16 reviews

$172
Average price / night
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Luxury Villa
Luxury Villa
Villa
Lancaster, NY, USA
2.9k from Depew center

Luxury, Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

3 Bedrooms5 Guests
8.8

Fabulous

17 reviews

$173
Average price / night
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Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo
Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo
House
Lancaster, NY, USA
3.6k from Depew center

Accommodations, Parking, Villas, Vacation homes, Spa, Cottages, Pet-friendly, Lodgings, Places to stay

3 Bedrooms9 Guests
New to Booking
$363
Average price / night
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Fireman's Park Quarters
Fireman's Park Quarters
House
Depew, NY, 14043, United States
1.1k from Depew center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

6 Bedrooms14 Guests
9.2

Superb

5 reviews

$424
Average price / night
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Spacious Buffalo Home Near Niagara Fall, Bills Stadium, Buffalo Airport
Spacious Buffalo Home Near Niagara Fall, Bills Stadium, Buffalo Airport
House
Depew, NY, USA
3.6k from Depew center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Vacation rentals

3 Bedrooms12 Guests
8.7

Fabulous

12 reviews

$437
Average price / night
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Renovated | Near Airport | Central Location
Renovated | Near Airport | Central Location
Apartment
Depew, NY, 14043, United States
1.3k from Depew center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

1 Bedroom4 Guests
9.0

Fabulous

24 reviews

$145
Average price / night
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Dog-Friendly Home about 14 Mi to Highmark Stadium
Dog-Friendly Home about 14 Mi to Highmark Stadium
House
Cheektowaga, NY, USA
4.1k from Depew center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Vacation rentals

3 Bedrooms9 Guests
9.2

Superb

5 reviews

$374
Average price / night
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Right in the village of depew on the center of the solar eclipse line
Right in the village of depew on the center of the solar eclipse line
House
Depew, NY, 14043, United States
1.6k from Depew center

Heater, Internet, Kitchen, No Smoking, TV

2 Bedrooms4 Guests
New to Booking
$810
Average price / night
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Sweet home
Sweet home
Apartment
Cheektowaga, NY, USA
4.8k from Depew center

Apartments, Cheap, Accommodations, Parking, Lodgings, Places to stay, Self-catering

3 Bedrooms6 Guests
10.0

Exceptional

1 reviews

$225
Average price / night
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13 Mi to Buffalo: Cozy Apartment in Depew!
13 Mi to Buffalo: Cozy Apartment in Depew!
Apartment
Depew, NY, 14043, United States
1.6k from Depew center

AC, Free Parking, Heater, Kitchen, Microwave, No Smoking, TV

1 Bedroom2 Guests
New to Booking
$203
Average price / night
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Family Fun Pool Central Airport
Family Fun Pool Central Airport
House
Williamsville, NY, USA
5.1k from Depew center

Security/Safety, Internet, View, Sports/Activities, Air Conditioner, Fireplace/Heating, Pet Friendly

1 Bedroom10 Guests
New to Booking
$546
Average price / night
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Charming Vacation Home Near Niagara Falls & Highmark Stadium
Charming Vacation Home Near Niagara Falls & Highmark Stadium
House
Depew, NY, 14043, United States
1.7k from Depew center

AC, Free Parking, Heater, Internet, Kitchen, Laundry, No Smoking, TV, Washer

3 Bedrooms6 Guests
9.6

Exceptional

4 reviews

$211
Average price / night
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9 Mi to Dtwn Buffalo Family Escape with Fenced Yard
9 Mi to Dtwn Buffalo Family Escape with Fenced Yard
House
Cheektowaga, NY, USA
5.4k from Depew center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

3 Bedrooms6 Guests
7.7

Good

3 reviews

$227
Average price / night
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Buffalo Niagara international airport 2 minutes away from the house
Buffalo Niagara international airport 2 minutes away from the house
Apartment
Cheektowaga, NY, 14225, United States
2.0k from Depew center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

3 Bedrooms7 Guests
6.8

Good

5 reviews

$339
Average price / night
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2 Mi to Walden Galleria Apartment with Patio
2 Mi to Walden Galleria Apartment with Patio
Apartment
Buffalo, NY, USA
5.5k from Depew center

Apartments, Accommodations, Parking, Pet-friendly, Lodgings, Places to stay

1 Bedroom2 Guests
New to Booking
$191
Average price / night
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Newly Remodeled! Upscale Home in Buffalo Suburbs
Newly Remodeled! Upscale Home in Buffalo Suburbs
House
Cheektowaga, NY, 14225, United States
2.1k from Depew center

AC, Dryer, Fireplace, Free Parking, Heater, Kitchen, Microwave, No Smoking, Outdoor Space

3 Bedrooms8 Guests
New to Booking
$263
Average price / night
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Nice & Lovely Family-Friendly Close to all
Nice & Lovely Family-Friendly Close to all
Apartment
Cheektowaga, NY, USA
6.3k from Depew center

Apartments, Accommodations, Parking, Lodgings, Places to stay

2 Bedrooms5 Guests
New to Booking
$223
Average price / night
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3-bedroom house in close to the airport Buffalo family- friendly no pets allowed
3-bedroom house in close to the airport Buffalo family- friendly no pets allowed
House
Depew, NY, 14043, United States
2.1k from Depew center

AC, Dryer, Fitness Equipment, Heater, Internet, Laundry, No Smoking, Washer

3 Bedrooms8 Guests
New to Booking
$211
Average price / night
Check Availability
Niagara Falls, Highmark, Buffalo Vacation House
Niagara Falls, Highmark, Buffalo Vacation House
House
Cheektowaga, NY, USA
6.5k from Depew center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

3 Bedrooms7 Guests
9.5

Superb

2 reviews

$207
Average price / night
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Best Parking AC Laundry BBQ Patio
Best Parking AC Laundry BBQ Patio
Apartment
Buffalo, NY, 14227, United States
2.5k from Depew center

AC, Heater, Laundry, No Smoking, Washer

1 Bedroom3 Guests
New to Booking
$339
Average price / night
Check Availability
Buffalo, NY 3 bedroom village home by carol
Buffalo, NY 3 bedroom village home by carol
Cottage
Lancaster, NY, 14086, United States
2.5k from Depew center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking

3 Bedrooms5 Guests
10.0

Exceptional

2 reviews

$367
Average price / night
Check Availability
Luxury Villa\n
Luxury Villa\n
House
Lancaster, NY, 14086, United States
2.6k from Depew center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking

3 Bedrooms5 Guests
9.6

Exceptional

10 reviews

$159
Average price / night
Check Availability
Charming 3-bedroom house with WiFi, AC in delightful Cheektowaga
Charming 3-bedroom house with WiFi, AC in delightful Cheektowaga
House
Buffalo, NY, 14225, United States
2.6k from Depew center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave

3 Bedrooms6 Guests
10.0

Exceptional

4 reviews

$326
Average price / night
Check Availability
3-bedroom house in delightful Cheektowaga with cool AC
3-bedroom house in delightful Cheektowaga with cool AC
House
Cheektowaga, NY, 14225, United States
2.6k from Depew center

AC, Dryer, Heater, Internet, Laundry, No Smoking, Washer

3 Bedrooms6 Guests
New to Booking
$206
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Vacation Rentals in Depew.

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Frequently Asked Questions

You can explore 153 verified vacation rentals in Depew. Our listings are sourced from a range of trusted providers, giving you access to a wide selection of private homes, apartments, and unique stays—all in one place.

Vacation rental prices in Depew vary depending on the season, property size, and location. Rates typically start from around $129 per night, with higher prices for larger homes or peak travel periods. Comparing available options can help you find a stay that matches both your budget and travel plans.

Most vacation rentals in Depew include fully equipped kitchens, making it easy to prepare meals and enjoy a more flexible stay. This is especially useful for families, longer stays, or travelers who prefer a home-like experience.

Yes, many vacation rentals in Depew welcome pets. Currently, 39 listings allow pets, although specific policies may vary by property. You can filter for pet-friendly options to quickly find suitable accommodations.

For popular travel periods such as holidays or peak seasons, it’s recommended to book your vacation rental 60 to 90 days in advance to secure the best options. During quieter times, you may still find good availability closer to your travel dates.

Vacation rentals in Depew often include amenities such as Internet, Fireplace/Heating, and Bedding/Linens. These features provide added comfort and convenience, making them a popular choice for travelers seeking more space and privacy.

You can use filters to narrow down your search by criteria such as number of bedrooms, guest ratings, or specific amenities like private pools or beachfront access. This makes it easier to find a property that fits your exact needs and preferences.