Short-Term Rentals in Mayo Clinic Florida, FL: Compare 10+ Sites & Save

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  6.  Mayo Clinic Florida

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1126 Best Short-Term Rentals in Mayo Clinic Florida (Starting from $112)

New Mins to Mayo Clinic Peaceful water views
New Mins to Mayo Clinic Peaceful water views
House
Jacksonville, FL, USA
0.9k from Mayo Clinic Florida center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

4 Bedrooms8 Guests
New to Booking
$173
Average price / night
Check Availability
Landing | Chic 1BD, Clubhouse
Landing | Chic 1BD, Clubhouse
Apartment
Jacksonville, FL, 32224, United States
0.3k from Mayo Clinic Florida center

AC, Heater, Internet, Kitchen, No Smoking, TV, Washer

1 Bedroom2 Guests
New to Booking
$276
Average price / night
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Canal-Front Retreat 4 Mi to Jacksonville Beach!
Canal-Front Retreat 4 Mi to Jacksonville Beach!
House
Jacksonville, FL, USA
0.9k from Mayo Clinic Florida center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

1 Bedroom8 Guests
New to Booking
$329
Average price / night
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Landing | Amazing 1BD, Clubhouse
Landing | Amazing 1BD, Clubhouse
Apartment
Jacksonville, FL, 32224, United States
0.3k from Mayo Clinic Florida center

AC, Heater, Internet, Kitchen, No Smoking, TV, Washer

1 Bedroom2 Guests
New to Booking
$284
Average price / night
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Palm Escape
Palm Escape
House
Jacksonville, FL, USA
1.4k from Mayo Clinic Florida center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

2 Bedrooms10 Guests
New to Booking
$811
Average price / night
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Landing | Modern 1BD, Clubhouse
Landing | Modern 1BD, Clubhouse
Apartment
Jacksonville, FL, 32224, United States
0.3k from Mayo Clinic Florida center

AC, Balcony, Heater, Internet, Kitchen, No Smoking, TV, Washer

1 Bedroom2 Guests
New to Booking
$282
Average price / night
Check Availability
5 Star Ultimate King Suite near Mayo
5 Star Ultimate King Suite near Mayo
Apartment
Jacksonville, FL, USA
1.8k from Mayo Clinic Florida center

Parking, Wheelchair Accessible, Balcony/Terrace, Hot Tub, Internet, Air Conditioner, Pool

2 Bedrooms4 Guests
New to Booking
$187
Average price / night
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NEW- The Cove at San Pablo- Across from the Mayo Clinic
NEW- The Cove at San Pablo- Across from the Mayo Clinic
House
Jacksonville, FL, 32224, United States
0.3k from Mayo Clinic Florida center

AC, Crib, Dryer, Free Parking, Internet, Kitchen, Laundry, Living Area, Microwave

3 Bedrooms6 Guests
10.0

Exceptional

25 reviews

$244
Average price / night
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Condo near Jax Beach and Mayo Clinic
Condo near Jax Beach and Mayo Clinic
Apartment
FL, USA
2.2k from Mayo Clinic Florida center

Apartments, Cheap, Accommodations, Pools, Parking, Lodgings, Hot tubs, Places to stay, Family

3 Bedrooms6 Guests
10.0

Exceptional

2 reviews

$153
Average price / night
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The Retreat close to Mayo Clinic!
The Retreat close to Mayo Clinic!
House
Jacksonville, FL, 32224, United States
0.4k from Mayo Clinic Florida center

AC, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms6 Guests
9.8

Exceptional

9 reviews

$233
Average price / night
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Great Condo near Beaches and Mayo Clinic
Great Condo near Beaches and Mayo Clinic
Apartment
Jacksonville, FL, USA
2.2k from Mayo Clinic Florida center

Apartments, Accommodations, Parking, Lodgings, Places to stay, Condos

3 Bedrooms6 Guests
New to Booking
$279
Average price / night
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Beautiful Coastal Home near Mayo Clinic. Pet Friendly!
Beautiful Coastal Home near Mayo Clinic. Pet Friendly!
House
Jacksonville, FL, 32224, United States
0.7k from Mayo Clinic Florida center

AC, Crib, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave

3 Bedrooms6 Guests
10.0

Exceptional

27 reviews

$295
Average price / night
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Be A Nomad - Close to Mayo & Beaches
Be A Nomad - Close to Mayo & Beaches
Apartment
FL, USA
2.3k from Mayo Clinic Florida center

Apartments, Accommodations, Parking, Lodgings, Places to stay

5 Bedrooms10 Guests
New to Booking
$219
Average price / night
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The Petite Retreat - Walk to Mayo Clinic!
The Petite Retreat - Walk to Mayo Clinic!
Apartment
Jacksonville, FL, 32224, United States
0.7k from Mayo Clinic Florida center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking

1 Bedroom2 Guests
10.0

Exceptional

17 reviews

$116
Average price / night
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Be A Nomad - Spacious Home close to Mayo & Beaches
Be A Nomad - Spacious Home close to Mayo & Beaches
Apartment
Jacksonville, FL, USA
2.3k from Mayo Clinic Florida center

Apartments, Accommodations, Parking, Lodgings, Places to stay

5 Bedrooms10 Guests
New to Booking
$627
Average price / night
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Pablo Pointe- Single Family Home directly across from the Mayo Clinic
Pablo Pointe- Single Family Home directly across from the Mayo Clinic
House
Jacksonville, FL, 32224, United States
0.7k from Mayo Clinic Florida center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking

3 Bedrooms6 Guests
9.6

Exceptional

9 reviews

$272
Average price / night
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Courtney Woods Oasis by SkyRun Jacksonville
Courtney Woods Oasis by SkyRun Jacksonville
House
Isle of Palms South, FL, USA
2.9k from Mayo Clinic Florida center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

1 Bedroom6 Guests
New to Booking
$282
Average price / night
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Jacksonville Home, Near Beach and Mayo Clinic!
Jacksonville Home, Near Beach and Mayo Clinic!
House
Jacksonville, FL, USA
2.9k from Mayo Clinic Florida center

Internet, Parking, Pet Friendly, Wheelchair Accessible, Pool, Child Friendly

3 Bedrooms6 Guests
New to Booking
$387
Average price / night
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Private Pool Getaway • 5min Beach • Sleeps 9
Private Pool Getaway • 5min Beach • Sleeps 9
House
Jacksonville, FL, 32250, United States
0.9k from Mayo Clinic Florida center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, No Smoking, Outdoor Space

4 Bedrooms9 Guests
10.0

Exceptional

2 reviews

$506
Average price / night
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Cozy Apt min to Mayo Beaches Free Wi-Fi Coffee Tea
Cozy Apt min to Mayo Beaches Free Wi-Fi Coffee Tea
Apartment
Jacksonville, FL, USA
3.0k from Mayo Clinic Florida center

Apartments, Cheap, Accommodations, Parking, Lodgings, Places to stay, Family, Self-catering

1 Bedroom4 Guests
10.0

Exceptional

2 reviews

$112
Average price / night
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Manatee House: Private Marsh View Retreat - 1 Mile to Mayo, 5 Miles to Beaches
Manatee House: Private Marsh View Retreat - 1 Mile to Mayo, 5 Miles to Beaches
House
Jacksonville, FL, 32224, United States
0.9k from Mayo Clinic Florida center

AC, Barbecue, Crib, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen

4 Bedrooms12 Guests
10.0

Exceptional

23 reviews

$480
Average price / night
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Beautiful Luxury House Great Location Near Beaches Mayo Clinic Shops Restaurants
Beautiful Luxury House Great Location Near Beaches Mayo Clinic Shops Restaurants
House
Jacksonville, FL, USA
3.5k from Mayo Clinic Florida center

Air Conditioner, Internet, Parking, Pool, Security/Safety, Child Friendly

2 Bedrooms5 Guests
New to Booking
$179
Average price / night
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1 Min to Mayo Clinic, 5 to Beach Luxury Suite with 2 King Beds
1 Min to Mayo Clinic, 5 to Beach Luxury Suite with 2 King Beds
Apartment
Jacksonville, FL, 32224, United States
1.0k from Mayo Clinic Florida center

AC, Balcony, Barbecue, Breakfast Available, Dryer, Free Parking, Heater, Internet, Kitchen

2 Bedrooms4 Guests
10.0

Exceptional

1 reviews

$317
Average price / night
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New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach
New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach
House
Jacksonville, FL, 32250, United States
1.0k from Mayo Clinic Florida center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, No Smoking

4 Bedrooms8 Guests
10.0

Exceptional

11 reviews

$629
Average price / night
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Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
House
Jacksonville, FL, 32250, United States
1.0k from Mayo Clinic Florida center

AC, Crib, Dryer, Fireplace, Fitness Equipment, Free Parking, Heater, Internet, Kitchen

4 Bedrooms8 Guests
9.4

Superb

78 reviews

$312
Average price / night
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Seabreeze Boating Way|Pool| Dock
Seabreeze Boating Way|Pool| Dock
House
Jacksonville, FL, 32250, United States
1.1k from Mayo Clinic Florida center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Living Area

2 Bedrooms4 Guests
New to Booking
$466
Average price / night
Check Availability
 Saltwater Pool I Firepits I Large Fenced Backyard I 4 Miles to Beach
Saltwater Pool I Firepits I Large Fenced Backyard I 4 Miles to Beach
House
Jacksonville, FL, 32250, United States
1.2k from Mayo Clinic Florida center

AC, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms6 Guests
9.8

Exceptional

14 reviews

$386
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Short-Term Rentals in Mayo Clinic Florida.

Where to stay in Mayo Clinic Florida? Best neighborhoods & areas

Mayo Clinic Florida Short-Term Rentals on the Map

Frequently Asked Questions

You can explore 1126 verified short-term rentals in Mayo Clinic Florida, including apartments, houses, and furnished stays suitable for both travel and temporary living.

Short-term rental prices in Mayo Clinic Florida vary depending on location, property size, and travel dates. Rates typically start from around $112 per night, with higher prices for premium properties or peak seasons.

Many short-term rentals in Mayo Clinic Florida include Wi-Fi, making them suitable for remote work. Some listings also provide dedicated workspaces, but it is recommended to check property details for specific features.

Booking 30 to 45 days in advance is generally recommended for the best availability. For peak travel periods or major events in Mayo Clinic Florida, booking earlier can help secure better options.

In many cases, utilities such as electricity, water, and internet are included in the rental price. However, this can vary by property, so it is important to review the listing details before booking.

Short-term rentals in Mayo Clinic Florida often include amenities such as Fireplace/Heating, Internet, and Laundry, providing a comfortable and convenient stay.

Short-term rentals in Mayo Clinic Florida are often used for flexible stays, including work trips or temporary housing, while vacation rentals are typically geared toward leisure stays in tourist areas. Both offer furnished, home-like accommodations.