Short-Term Rentals in Looe Key National Marine Sanctuary, FL: Compare 10+ Sites & Save

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264 Best Short-Term Rentals in Looe Key National Marine Sanctuary (Starting from $178)

Fishermen`s Paradise
Fishermen`s Paradise
House
Big Pine Key, FL, USA
1.7k from Looe Key National Marine Sanctuary center

Accommodations, Pools, Villas, Vacation homes, Cottages, Lodgings, Places to stay, Family

3 Bedrooms8 Guests
9.0

Fabulous

1 reviews

$1127
Average price / night
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Open 360 water view,  boat dockage, 4 bedroom Home in Big Pine Key
Open 360 water view, boat dockage, 4 bedroom Home in Big Pine Key
House
Big Pine Key, FL, 33043, United States
0.4k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Fitness Equipment, Free Parking, Heater, Internet, Kitchen

4 Bedrooms10 Guests
10.0

Exceptional

2 reviews

$623
Average price / night
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Tiki Beach - Big Pine Key
Tiki Beach - Big Pine Key
House
Big Pine Key, FL, USA
1.7k from Looe Key National Marine Sanctuary center

Pool, Parking, Security/Safety, View, Sports/Activities, Spa, Barbecue/Outdoor Cooking

4 Bedrooms10 Guests
New to Booking
$831
Average price / night
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3bd/2.5 bath comfortable home with large dock located on a direct access canal!
3bd/2.5 bath comfortable home with large dock located on a direct access canal!
House
Big Pine Key, FL, 33043, United States
0.5k from Looe Key National Marine Sanctuary center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Laundry, Living Area, Microwave

3 Bedrooms9 Guests
2.0

Review score

1 reviews

$359
Average price / night
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Old Wooden Bridge Resort & Marina
Old Wooden Bridge Resort & Marina
Cabin
Big Pine Key, FL, USA
1.8k from Looe Key National Marine Sanctuary center

Accommodations, Pools, Parking, Lodges, Cabins, Pet-friendly, Lodgings, Places to stay

43 Bedrooms138 Guests
8.4

Very Good

241 reviews

$257
Average price / night
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Lost  At Atlantis
Lost At Atlantis
House
Big Pine Key, FL, 33043, United States
0.8k from Looe Key National Marine Sanctuary center

AC, Barbecue, Dryer, Free Parking, Internet, Kitchen, Laundry, Living Area, Microwave

3 Bedrooms6 Guests
New to Booking
$273
Average price / night
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Hellenga Haven
Hellenga Haven
House
Big Pine Key, FL, USA
2.0k from Looe Key National Marine Sanctuary center

Accommodations, Pools, Villas, Vacation homes, Cottages, Lodgings, Places to stay

3 Bedrooms8 Guests
New to Booking
$411
Average price / night
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3 BR Canal Home in Big Pine Key, FL - Private Pool/Spa - Great Boating Access!!!
3 BR Canal Home in Big Pine Key, FL - Private Pool/Spa - Great Boating Access!!!
House
Big Pine Key, FL, 33043, United States
0.8k from Looe Key National Marine Sanctuary center

AC, Barbecue, Dryer, Free Parking, Heater, Hot Tub, Internet, Kitchen, Laundry

3 Bedrooms6 Guests
New to Booking
$259
Average price / night
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Sunset Villa
Sunset Villa
House
Big Pine Key, FL, USA
2.1k from Looe Key National Marine Sanctuary center

Accommodations, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Vacation rentals, Places to stay

3 Bedrooms6 Guests
New to Booking
$210
Average price / night
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Yeya's Hideaway | 4 bedrooms, POOL on the way by 2027!
Yeya's Hideaway | 4 bedrooms, POOL on the way by 2027!
House
Big Pine Key, FL, 33043, United States
0.8k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Heater, Internet, Kitchen, Laundry, Microwave

4 Bedrooms12 Guests
New to Booking
$490
Average price / night
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Big Pine Key Dreams
Big Pine Key Dreams
House
Big Pine Key, FL, USA
2.1k from Looe Key National Marine Sanctuary center

Accommodations, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals, Places to stay, Accessible hotels

2 Bedrooms6 Guests
New to Booking
$263
Average price / night
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Stunning 5 Bedroom Open Water Pool Home With Great Boating
Stunning 5 Bedroom Open Water Pool Home With Great Boating
House
Big Pine Key, FL, 33043, United States
0.8k from Looe Key National Marine Sanctuary center

AC, Dryer, Heater, Laundry, No Smoking, Washer

5 Bedrooms10 Guests
New to Booking
$1021
Average price / night
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key Deer Retreat/direct gulf access/hot tub
key Deer Retreat/direct gulf access/hot tub
House
Big Pine Key, FL, USA
2.4k from Looe Key National Marine Sanctuary center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

2 Bedrooms7 Guests
10.0

Exceptional

3 reviews

$310
Average price / night
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Peaceful Big Pine Tropical Seaside-BP#22
Peaceful Big Pine Tropical Seaside-BP#22
House
Big Pine Key, FL, 33043, United States
0.9k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Free Parking, Internet, Laundry, Living Area, Microwave

3 Bedrooms8 Guests
New to Booking
$274
Average price / night
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RV In The Keys a Tropical Retreat
RV In The Keys a Tropical Retreat
House
Big Pine Key, FL, USA
2.8k from Looe Key National Marine Sanctuary center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

1 Bedroom4 Guests
New to Booking
$178
Average price / night
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Captain & Mermaid's Diamond #BP25
Captain & Mermaid's Diamond #BP25
House
Big Pine Key, FL, 33043, United States
0.9k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Extra Bed, Free Parking, Internet, Kitchen, Laundry

1 Bedroom4 Guests
New to Booking
$196
Average price / night
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Florida Keys /Big Pine Key/ Dear Haven
Florida Keys /Big Pine Key/ Dear Haven
Apartment
Looe Key National Marine Sanctuary, Big Pine Key, Florida, USA
2.8k from Looe Key National Marine Sanctuary center

Air Conditioner, Parking

2 Bedrooms4 Guests
New to Booking
$7000
Average price / night
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Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!
Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!
House
Big Pine Key, FL, 33043, United States
0.9k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

3 Bedrooms6 Guests
10.0

Exceptional

34 reviews

$330
Average price / night
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Cedar Cottage
Cedar Cottage
House
Big Pine Key, FL, USA
3.8k from Looe Key National Marine Sanctuary center

Accommodations, Villas, Vacation homes, Cottages, Lodgings, Places to stay

2 Bedrooms4 Guests
New to Booking
$184
Average price / night
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Waterfront Home in The Fabulous Florida Keys with Peak-A-Boo Views of the Bay!
Waterfront Home in The Fabulous Florida Keys with Peak-A-Boo Views of the Bay!
House
Big Pine Key, FL, 33043, United States
0.9k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Free Parking, Internet, Kitchen, Laundry, Living Area

2 Bedrooms6 Guests
9.6

Exceptional

14 reviews

$209
Average price / night
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Tarpon Tales | Fantastic boating, pet-friendly
Tarpon Tales | Fantastic boating, pet-friendly
House
Big Pine Key, FL, 33043, United States
0.9k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Extra Bed, Internet, Kitchen, Laundry, Microwave

2 Bedrooms4 Guests
10.0

Exceptional

1 reviews

$233
Average price / night
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Family friendly canal home,150 ft dock, easy access to Atl & Gulf
Family friendly canal home,150 ft dock, easy access to Atl & Gulf
House
Big Pine Key, FL, 33043, United States
0.9k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen

5 Bedrooms13 Guests
10.0

Exceptional

1 reviews

$538
Average price / night
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Florida Keys Water Front Vacation Home with Pool
Florida Keys Water Front Vacation Home with Pool
House
Big Pine Key, FL, 33043, United States
0.9k from Looe Key National Marine Sanctuary center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave

3 Bedrooms6 Guests
New to Booking
$296
Average price / night
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The Friendly Pelican\n2-BDR 2-BATH on a canal w/AC in Big Pine Key
The Friendly Pelican\n2-BDR 2-BATH on a canal w/AC in Big Pine Key
House
Big Pine Key, FL, 33043, United States
1.0k from Looe Key National Marine Sanctuary center

AC, Barbecue, Dryer, Free Parking, Laundry, Living Area, Microwave, No Smoking, TV

2 Bedrooms6 Guests
New to Booking
$196
Average price / night
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Mickey and Lynn's House of Windows
Mickey and Lynn's House of Windows
House
Big Pine Key, FL, 33050, United States
1.0k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Dryer, Fireplace, Free Parking, Heater, Hot Tub, Internet

3 Bedrooms7 Guests
10.0

Exceptional

8 reviews

$403
Average price / night
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Boater's Paradise with Boat Dock / Quick Open Water Access
Boater's Paradise with Boat Dock / Quick Open Water Access
House
Big Pine Key, FL, 33043, United States
1.1k from Looe Key National Marine Sanctuary center

AC, Internet, Laundry, No Smoking, Outdoor Grill, TV, Washer

2 Bedrooms4 Guests
8.0

Good

3 reviews

$227
Average price / night
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Upscale ocean front home & easy canal boat access to Gulf or Atlantic
Upscale ocean front home & easy canal boat access to Gulf or Atlantic
House
Big Pine Key, FL, 33043, United States
1.1k from Looe Key National Marine Sanctuary center

AC, Balcony, Barbecue, Crib, Dryer, Extra Bed, Fireplace, Fitness Equipment, Free Parking

3 Bedrooms6 Guests
10.0

Exceptional

4 reviews

$293
Average price / night
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Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Short-Term Rentals in Looe Key National Marine Sanctuary.

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Looe Key National Marine Sanctuary Short-Term Rentals on the Map

Frequently Asked Questions

You can explore 264 verified short-term rentals in Looe Key National Marine Sanctuary, including apartments, houses, and furnished stays suitable for both travel and temporary living.

Short-term rental prices in Looe Key National Marine Sanctuary vary depending on location, property size, and travel dates. Rates typically start from around $178 per night, with higher prices for premium properties or peak seasons.

Many short-term rentals in Looe Key National Marine Sanctuary include Wi-Fi, making them suitable for remote work. Some listings also provide dedicated workspaces, but it is recommended to check property details for specific features.

Booking 30 to 45 days in advance is generally recommended for the best availability. For peak travel periods or major events in Looe Key National Marine Sanctuary, booking earlier can help secure better options.

In many cases, utilities such as electricity, water, and internet are included in the rental price. However, this can vary by property, so it is important to review the listing details before booking.

Short-term rentals in Looe Key National Marine Sanctuary often include amenities such as Laundry, Internet, and Kitchen, providing a comfortable and convenient stay.

Short-term rentals in Looe Key National Marine Sanctuary are often used for flexible stays, including work trips or temporary housing, while vacation rentals are typically geared toward leisure stays in tourist areas. Both offer furnished, home-like accommodations.