Short-Term Rentals in Isle of Palms, FL: Compare 10+ Sites & Save

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  6.  Isle of Palms

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1123 Best Short-Term Rentals in Isle of Palms (Starting from $153)

New Mins to Mayo Clinic Peaceful water views
New Mins to Mayo Clinic Peaceful water views
House
Jacksonville, FL, USA
0.4k from Isle of Palms center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

4 Bedrooms8 Guests
New to Booking
$173
Average price / night
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Seabreeze Boating Way|Pool| Dock
Seabreeze Boating Way|Pool| Dock
House
Jacksonville, FL, 32250, United States
0.2k from Isle of Palms center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Living Area

2 Bedrooms4 Guests
New to Booking
$466
Average price / night
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Canal-Front Retreat 4 Mi to Jacksonville Beach!
Canal-Front Retreat 4 Mi to Jacksonville Beach!
House
Jacksonville, FL, USA
0.4k from Isle of Palms center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

1 Bedroom8 Guests
New to Booking
$329
Average price / night
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Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
House
Jacksonville, FL, 32250, United States
0.3k from Isle of Palms center

AC, Crib, Dryer, Fireplace, Fitness Equipment, Free Parking, Heater, Internet, Kitchen

4 Bedrooms8 Guests
9.4

Superb

78 reviews

$312
Average price / night
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Palm Escape
Palm Escape
House
Jacksonville, FL, USA
0.5k from Isle of Palms center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

2 Bedrooms10 Guests
New to Booking
$811
Average price / night
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Mayo Clinic 1.8 miles #2 Your Home Away From Home
Mayo Clinic 1.8 miles #2 Your Home Away From Home
House
Jacksonville Beach, FL, 32250, United States
0.3k from Isle of Palms center

AC, Dryer, Free Parking, Heater, Internet, Laundry, No Smoking, Washer

3 Bedrooms5 Guests
9.6

Exceptional

8 reviews

$367
Average price / night
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5 Star Ultimate King Suite near Mayo
5 Star Ultimate King Suite near Mayo
Apartment
Jacksonville, FL, USA
1.2k from Isle of Palms center

Parking, Wheelchair Accessible, Balcony/Terrace, Hot Tub, Internet, Air Conditioner, Pool

2 Bedrooms4 Guests
New to Booking
$187
Average price / night
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Be A Nomad - Close to Mayo & Beaches
Be A Nomad - Close to Mayo & Beaches
Apartment
FL, USA
1.8k from Isle of Palms center

Apartments, Accommodations, Parking, Lodgings, Places to stay

5 Bedrooms10 Guests
New to Booking
$219
Average price / night
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Private Pool Getaway • 5min Beach • Sleeps 9
Private Pool Getaway • 5min Beach • Sleeps 9
House
Jacksonville, FL, 32250, United States
0.4k from Isle of Palms center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, No Smoking, Outdoor Space

4 Bedrooms9 Guests
10.0

Exceptional

2 reviews

$506
Average price / night
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Be A Nomad - Spacious Home close to Mayo & Beaches
Be A Nomad - Spacious Home close to Mayo & Beaches
Apartment
Jacksonville, FL, USA
1.8k from Isle of Palms center

Apartments, Accommodations, Parking, Lodgings, Places to stay

5 Bedrooms10 Guests
New to Booking
$627
Average price / night
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Your Home Away From Home and 2 miles from The Mayo Clinic and Snowbirds welcomed
Your Home Away From Home and 2 miles from The Mayo Clinic and Snowbirds welcomed
House
Jacksonville, FL, 32250, United States
0.4k from Isle of Palms center

AC, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

3 Bedrooms6 Guests
8.8

Fabulous

5 reviews

$353
Average price / night
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Courtney Woods Oasis by SkyRun Jacksonville
Courtney Woods Oasis by SkyRun Jacksonville
House
Isle of Palms South, FL, USA
2.2k from Isle of Palms center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

1 Bedroom6 Guests
New to Booking
$282
Average price / night
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Lux Pool Home Close to Mayo & Jacksonville Beach!
Lux Pool Home Close to Mayo & Jacksonville Beach!
House
Jacksonville, FL, 32250, United States
0.4k from Isle of Palms center

AC, Dryer, Heater, Internet, Kitchen, Laundry, No Smoking, Pool, TV

3 Bedrooms6 Guests
10.0

Exceptional

9 reviews

$349
Average price / night
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Jacksonville Home, Near Beach and Mayo Clinic!
Jacksonville Home, Near Beach and Mayo Clinic!
House
Jacksonville, FL, USA
2.3k from Isle of Palms center

Internet, Parking, Pet Friendly, Wheelchair Accessible, Pool, Child Friendly

3 Bedrooms6 Guests
New to Booking
$387
Average price / night
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Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
House
Jacksonville, FL, 32250, United States
0.4k from Isle of Palms center

AC, Arcade, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

4 Bedrooms10 Guests
9.8

Exceptional

38 reviews

$320
Average price / night
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Beach Retreat in Jacksonville PetandFamily-Friendly
Beach Retreat in Jacksonville PetandFamily-Friendly
House
Jacksonville Beach, FL, USA
2.5k from Isle of Palms center

Accommodations, Parking, Villas, Vacation homes, Spa, Cottages, Pet-friendly, Lodgings, Vacation rentals

4 Bedrooms12 Guests
7.5

Good

4 reviews

$813
Average price / night
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5 min to Mayo—luxury, comfort & care designed for patients & caregivers.
5 min to Mayo—luxury, comfort & care designed for patients & caregivers.
House
Jacksonville Beach, FL, 32250, United States
0.5k from Isle of Palms center

AC, Barbecue, Fireplace, Fitness Equipment, Free Parking, Heater, Internet, Living Area, Microwave

3 Bedrooms8 Guests
10.0

Exceptional

1 reviews

$707
Average price / night
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Taj Duval, Sleeps 14, Pool, Lux
Taj Duval, Sleeps 14, Pool, Lux
House
Jacksonville Beach, FL, USA
2.6k from Isle of Palms center

Accommodations, Villas, Vacation homes, Spa, Cottages, Pet-friendly, Lodgings, Places to stay, Family

5 Bedrooms14 Guests
New to Booking
$1852
Average price / night
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SMV Palm Escape Retreat nr Mayo
SMV Palm Escape Retreat nr Mayo
House
Jacksonville, FL, 32250, United States
0.5k from Isle of Palms center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry

4 Bedrooms10 Guests
10.0

Exceptional

2 reviews

$648
Average price / night
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Condo near Jax Beach and Mayo Clinic
Condo near Jax Beach and Mayo Clinic
Apartment
FL, USA
2.9k from Isle of Palms center

Apartments, Cheap, Accommodations, Pools, Parking, Lodgings, Hot tubs, Places to stay, Family

3 Bedrooms6 Guests
10.0

Exceptional

2 reviews

$153
Average price / night
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 Saltwater Pool I Firepits I Large Fenced Backyard I 4 Miles to Beach
Saltwater Pool I Firepits I Large Fenced Backyard I 4 Miles to Beach
House
Jacksonville, FL, 32250, United States
0.6k from Isle of Palms center

AC, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms6 Guests
9.8

Exceptional

14 reviews

$386
Average price / night
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Great Condo near Beaches and Mayo Clinic
Great Condo near Beaches and Mayo Clinic
Apartment
Jacksonville, FL, USA
2.9k from Isle of Palms center

Apartments, Accommodations, Parking, Lodgings, Places to stay, Condos

3 Bedrooms6 Guests
New to Booking
$279
Average price / night
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New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach
New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach
House
Jacksonville, FL, 32250, United States
0.6k from Isle of Palms center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, No Smoking

4 Bedrooms8 Guests
10.0

Exceptional

11 reviews

$629
Average price / night
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Reel Relaxed | Team Joseph Ellen
Reel Relaxed | Team Joseph Ellen
House
Jacksonville Beach, FL, 32250, United States
0.6k from Isle of Palms center

AC, Balcony, Barbecue, Dryer, Heater, Hot Tub, Internet, Kitchen, Microwave

3 Bedrooms8 Guests
New to Booking
$443
Average price / night
Check Availability
North Star Hideaway - Discover a hidden gem close to Jacksonville Beach, FL.
North Star Hideaway - Discover a hidden gem close to Jacksonville Beach, FL.
House
Jacksonville, FL, 32250, United States
0.6k from Isle of Palms center

AC, Dryer, Heater, Laundry, No Smoking, Washer

4 Bedrooms8 Guests
New to Booking
$299
Average price / night
Check Availability
Family-Friendly Jax Beach Retreat with Heated Pool
Family-Friendly Jax Beach Retreat with Heated Pool
House
Jacksonville Beach, FL, 32250, United States
0.6k from Isle of Palms center

AC, Arcade, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet

4 Bedrooms8 Guests
10.0

Exceptional

36 reviews

$495
Average price / night
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Tres Palmas!Renovated Pool Home Near Mayo & Beach!
Tres Palmas!Renovated Pool Home Near Mayo & Beach!
House
Jacksonville, FL, 32250, United States
0.7k from Isle of Palms center

AC, Balcony, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

4 Bedrooms6 Guests
9.8

Exceptional

12 reviews

$620
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Short-Term Rentals in Isle of Palms.

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Isle of Palms Short-Term Rentals on the Map

Frequently Asked Questions

You can explore 1123 verified short-term rentals in Isle of Palms, including apartments, houses, and furnished stays suitable for both travel and temporary living.

Short-term rental prices in Isle of Palms vary depending on location, property size, and travel dates. Rates typically start from around $153 per night, with higher prices for premium properties or peak seasons.

Many short-term rentals in Isle of Palms include Wi-Fi, making them suitable for remote work. Some listings also provide dedicated workspaces, but it is recommended to check property details for specific features.

Booking 30 to 45 days in advance is generally recommended for the best availability. For peak travel periods or major events in Isle of Palms, booking earlier can help secure better options.

In many cases, utilities such as electricity, water, and internet are included in the rental price. However, this can vary by property, so it is important to review the listing details before booking.

Short-term rentals in Isle of Palms often include amenities such as Fireplace/Heating, Internet, and Laundry, providing a comfortable and convenient stay.

Short-term rentals in Isle of Palms are often used for flexible stays, including work trips or temporary housing, while vacation rentals are typically geared toward leisure stays in tourist areas. Both offer furnished, home-like accommodations.