Hotels in Santo Domingo, Mexico City: Compare 10+ Sites & Save

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  3.  Mexico

  4.  Mexico City
  5.  Santo Domingo

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389 Best Hotels in Santo Domingo (Starting from $50)

Los Camilos
Los Camilos
Hotel
Mexico City, Mexico
2.2k from Santo Domingo center

Accommodations, Pet-friendly, Lodgings, Places to stay

7.2

Good

199 reviews

$133
Average price / night
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H21 Hospedaje Boutique
H21 Hospedaje Boutique
Hotel
21 Higuera La Concepción, Mexico City, 04020, Mexico
2.3k from Santo Domingo center

AC, Free Parking, Frontdesk 24 Hour, Heater, Housekeeping, Internet, Laundry, No Smoking

10.0

Exceptional

216 reviews

$241
Average price / night
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Siete Puertas Coyoacán
Siete Puertas Coyoacán
Hotel
Santo Domingo, Mexico City, Mexico
2.4k from Santo Domingo center

Accommodations, Pet-friendly, Lodgings, Places to stay, Family

8.5

Very Good

82 reviews

$89
Average price / night
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Casa Tonal
Casa Tonal
Hotel
7 Vallarta La Concepción, Mexico City, 04000, Mexico
2.5k from Santo Domingo center

Breakfast Available, Business Services, Frontdesk 24 Hour, Housekeeping, Internet, Laundry, Outdoor Space, Spa

9.4

Superb

41 reviews

$97
Average price / night
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Tonalli Casa Boutique
Tonalli Casa Boutique
Hotel
Mexico City, Mexico
2.5k from Santo Domingo center

Cheap, Accommodations, Spa, 4-star, Lodgings, Places to stay, Self-catering

8.8

Fabulous

101 reviews

$95
Average price / night
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Hotel Boutique Casa Alebrije
Hotel Boutique Casa Alebrije
Hotel
16 Cda. Belisario Domínguez Del Carmen, Mexico City, 04100, Mexico
2.6k from Santo Domingo center

AC, Business Services, Crib, Extra Bed, Frontdesk 24 Hour, Heater, Housekeeping, Internet, Laundry

10.0

Exceptional

95 reviews

$178
Average price / night
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Suite Deluxe Doble Queen - 05
Suite Deluxe Doble Queen - 05
Hotel
CDMX, 04100, Mexico
2.6k from Santo Domingo center

AC, Balcony, Breakfast Included, Crib, Heater, No Smoking, Outdoor Space, Toys, TV

New to Booking
$1245
Average price / night
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Agata Hotel Boutique & Spa
Agata Hotel Boutique & Spa
Hotel
Mexico City, Mexico
2.6k from Santo Domingo center

Luxury, Accommodations, Spa, 5-star, Lodgings, Places to stay, Family

9.2

Superb

198 reviews

$140
Average price / night
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Suite Deluxe King - 07
Suite Deluxe King - 07
Hotel
CDMX, 04100, Mexico
2.6k from Santo Domingo center

AC, Balcony, Breakfast Included, Crib, Heater, Internet, No Smoking, Outdoor Space, Toys

New to Booking
$1095
Average price / night
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Meztli: Casa Boutique & Spa
Meztli: Casa Boutique & Spa
Hotel
Mexico City, Mexico
2.8k from Santo Domingo center

Cheap, Accommodations, Parking, Spa, Pet-friendly, 4-star, Lodgings, Places to stay, Family

8.5

Very Good

184 reviews

$101
Average price / night
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Hotel Casa Alebrije: Junior Suite King - 02
Hotel Casa Alebrije: Junior Suite King - 02
Hotel
CDMX, 04100, Mexico
2.6k from Santo Domingo center

AC, Balcony, Breakfast Included, Crib, Heater, Internet, No Smoking, Outdoor Space, Toys

New to Booking
$1138
Average price / night
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Hotel Jard Inn Adult Only
Hotel Jard Inn Adult Only
Hotel
Santo Domingo, Mexico City, Mexico
2.8k from Santo Domingo center

Laundry, Internet, Air Conditioner, Parking

7.0

Good

69 reviews

$54
Average price / night
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Hotel Casa Alebrije: Junior Suite King - 01
Hotel Casa Alebrije: Junior Suite King - 01
Hotel
CDMX, 04100, Mexico
2.6k from Santo Domingo center

AC, Breakfast Included, Crib, Heater, No Smoking, Outdoor Space, Toys, TV

New to Booking
$1120
Average price / night
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One Periferico Sur
One Periferico Sur
Hotel
Mexico City, Mexico
2.9k from Santo Domingo center

Cheap, Accommodations, Parking, 3-star, Lodgings, Places to stay, Accessible hotels

8.5

Very Good

1254 reviews

$67
Average price / night
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Suite Deluxe Doble Queen - 04
Suite Deluxe Doble Queen - 04
Hotel
CDMX, 04100, Mexico
2.6k from Santo Domingo center

AC, Breakfast Included, Crib, Heater, Internet, No Smoking, Outdoor Space, Toys, TV

New to Booking
$1119
Average price / night
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La Casita de Coyoacán
La Casita de Coyoacán
Hotel
Mexico City, Mexico
2.9k from Santo Domingo center

B&bs, Cheap, Accommodations, Parking, Inns, Lodgings, Places to stay, Family

8.9

Fabulous

303 reviews

$50
Average price / night
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Hotel Casa Alebrije: Suite Deluxe Doble Queen - 03
Hotel Casa Alebrije: Suite Deluxe Doble Queen - 03
Hotel
CDMX, 04100, Mexico
2.6k from Santo Domingo center

AC, Balcony, Breakfast Included, Crib, Heater, No Smoking, Outdoor Space, Toys, TV

New to Booking
$1215
Average price / night
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Fiesta Inn Periferico Sur
Fiesta Inn Periferico Sur
Hotel
Mexico City, Mexico
2.9k from Santo Domingo center

Cheap, Accommodations, Pools, Parking, 4-star, Lodgings, Places to stay, Accessible hotels

8.5

Very Good

1237 reviews

$138
Average price / night
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Suite Deluxe Doble Queen - 06
Suite Deluxe Doble Queen - 06
Hotel
CDMX, 04100, Mexico
2.6k from Santo Domingo center

AC, Breakfast Included, Crib, Heater, No Smoking, Outdoor Space, Toys, TV

New to Booking
$1068
Average price / night
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Hotel Montreal
Hotel Montreal
Hotel
Mexico City, Mexico
2.9k from Santo Domingo center

Breakfast, Parking, Wheelchair Accessible, Internet

7.8

Good

165 reviews

$51
Average price / night
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Hotel Finisterre
Hotel Finisterre
Hotel
Santo Domingo, Mexico City, Mexico
2.9k from Santo Domingo center

Accommodations, Parking, Lodgings, Hot tubs, Places to stay, Accessible hotels

7.6

Good

643 reviews

$284
Average price / night
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Chalet del Carmen, Coyoacán
Chalet del Carmen, Coyoacán
Hotel
Mexico City, Mexico
3.0k from Santo Domingo center

Cheap, Accommodations, Lodgings, Places to stay, Accessible hotels

9.1

Superb

114 reviews

$72
Average price / night
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Casa Hidalgo
Casa Hidalgo
Hotel
167 Av Miguel Hidalgo Del Carmen, Mexico City, 04100, Mexico
2.7k from Santo Domingo center

Arcade, Barbecue, Breakfast Available, Free Parking, Internet, Kitchen, Laundry, Microwave, No Smoking

7.8

Good

48 reviews

$59
Average price / night
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Mina 32 - Coyoacan
Mina 32 - Coyoacan
Hotel
Mexico City, Mexico
3.0k from Santo Domingo center

Cheap, Accommodations, Lodgings, Places to stay

9.0

Fabulous

293 reviews

$84
Average price / night
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Hotel Jard Inn Adults only
Hotel Jard Inn Adults only
Hotel
2376 Calz. de Tlalpan El Centinela, Mexico City, 4450, Mexico
2.8k from Santo Domingo center

AC, Elevator, Free Parking, Frontdesk 24 Hour, Internet, No Smoking, Room Service, TV

6.6

Good

83 reviews

$58
Average price / night
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Suites Perisur Apartamentos Amueblados
Suites Perisur Apartamentos Amueblados
Hotel
Mexico City, Mexico
3.1k from Santo Domingo center

Luxury, Cheap, Accommodations, Parking, Romantic, 4-star, Lodgings, Hot tubs, Places to stay

9.3

Superb

582 reviews

$127
Average price / night
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Hotel Real del Sur
Hotel Real del Sur
Hotel
Mexico City, Mexico
3.2k from Santo Domingo center

Accommodations, Parking, Spa, Romantic, 4-star, Lodgings, Hot tubs, Places to stay, Accessible hotels

8.1

Very Good

1154 reviews

$65
Average price / night
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Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Hotels in Santo Domingo.

Stay Near Santo Domingo's Top Attractions

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Santo Domingo Hotels on the Map

Frequently Asked Questions

You can explore 389 verified hotels in Santo Domingo. These include a range of options from luxury resorts and boutique hotels to budget-friendly accommodations suitable for different travel styles.

Hotel prices in Santo Domingo vary depending on the season, location, and property type. Rates typically start from around $50 per night, with higher prices for premium hotels, central locations, or peak travel dates.

Most hotels in Santo Domingo include amenities such as Child Friendly, Guest Services, and Entertainment. Additional features like breakfast, parking, or resort facilities may vary by property, so it’s helpful to review the details before booking.

You can identify top-rated hotels in Santo Domingo by sorting listings based on guest ratings and reviews. Looking at recent feedback, overall scores, and review volume can help you find properties that consistently deliver a high-quality experience.

For popular travel periods or busy locations, booking 30 to 60 days in advance is generally recommended to secure preferred options. During quieter periods, you may find more flexibility and availability closer to your travel dates.

Yes, some hotels in Santo Domingo welcome pets. Currently, 8 listings allow pets, although policies may vary. It’s a good idea to review any pet-related rules before booking.

Many hotels in Santo Domingo offer flexible or refundable booking options. Checking the cancellation policy before confirming your reservation can help you choose a rate that suits your travel plans.