Hotels in Lester E. Cox Medical Center South, MO: Compare 10+ Sites & Save

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64 Best Hotels in Lester E. Cox Medical Center South (Starting from $62)

The Bradford Hotel, an Ascend Collection Hotel
The Bradford Hotel, an Ascend Collection Hotel
Hotel
Springfield, MO, USA
0.5k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Lodgings, Places to stay, Accessible hotels

8.2

Very Good

186 reviews

$99
Average price / night
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Residence Inn Springfield
Residence Inn Springfield
Hotel
Springfield, MO, USA
0.8k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Family

8.7

Fabulous

161 reviews

$118
Average price / night
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Residence Inn by Marriott Springfield
Residence Inn by Marriott Springfield
Hotel
1303 E Kingsley St, Springfield, MO, 65804, United States
0.8k from Lester E. Cox Medical Center South center

AC, Balcony, Barbecue, Breakfast Included, Business Services, Crib, Elevator, Fitness Equipment, Frontdesk 24 Hour

9.0

Fabulous

989 reviews

$148
Average price / night
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Extended Stay America Select Suites - Springfield - South
Extended Stay America Select Suites - Springfield - South
Hotel
Springfield, MO, USA
0.8k from Lester E. Cox Medical Center South center

Accommodations, Parking, Lodgings, Places to stay, Self-catering, Accessible hotels

6.5

Good

273 reviews

$91
Average price / night
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Candlewood Suites Springfield-Medical District
Candlewood Suites Springfield-Medical District
Hotel
1035 E Republic Rd, Springfield, MO, 65807, United States
0.9k from Lester E. Cox Medical Center South center

AC, Barbecue, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Grocery, Housekeeping

9.2

Superb

415 reviews

$133
Average price / night
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Candlewood Suites Springfield-Medical District by IHG
Candlewood Suites Springfield-Medical District by IHG
Hotel
Springfield, MO, USA
0.9k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Parking, 3-star, Lodgings, Places to stay, Self-catering, Accessible hotels

8.5

Very Good

75 reviews

$111
Average price / night
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Homewood Suites By Hilton Springfield Medical District
Homewood Suites By Hilton Springfield Medical District
Hotel
MO, USA
1.4k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Hilton , Pet-friendly, 3-star, Lodgings, Places to stay

8.7

Fabulous

328 reviews

$131
Average price / night
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Element Springfield South
Element Springfield South
Hotel
Springfield, MO, USA
1.6k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Lodgings, Places to stay, Family, Self-catering, Accessible hotels

9.0

Fabulous

33 reviews

$124
Average price / night
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MainStay Suites Springfield South - Battlefield Rd
MainStay Suites Springfield South - Battlefield Rd
Hotel
Springfield, MO, USA
1.6k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Parking, Pet-friendly, Lodgings, Places to stay, Family, Self-catering, Accessible hotels

8.2

Very Good

238 reviews

$99
Average price / night
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Holiday Inn Express and Suites Springfield Medical District by IHG
Holiday Inn Express and Suites Springfield Medical District by IHG
Hotel
310 E Monastery, Springfield, MO, 65801, United States
1.6k from Lester E. Cox Medical Center South center

AC, Breakfast Included, Business Services, Crib, Elevator, Extra Bed, Fitness Equipment, Free Parking, Frontdesk 24 Hour

9.4

Superb

979 reviews

$158
Average price / night
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Sleep Inn Springfield South I60 near Medical District
Sleep Inn Springfield South I60 near Medical District
Hotel
233 E Camino Alto, Springfield, MO, 65810, United States
1.8k from Lester E. Cox Medical Center South center

AC, Breakfast Included, Business Services, Elevator, Free Parking, Frontdesk 24 Hour, Hot Tub, Internet, Outdoor Space

8.2

Very Good

861 reviews

$109
Average price / night
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Hampton Inn Springfield-South
Hampton Inn Springfield-South
Hotel
3232 S. Glenstone, Springfield, MO, 65804, United States
2.0k from Lester E. Cox Medical Center South center

AC, Breakfast Included, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Housekeeping, Internet, Laundry

9.4

Superb

650 reviews

$115
Average price / night
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Comfort Inn South - Springfield
Comfort Inn South - Springfield
Hotel
3776 S Glenstone Avenue, Springfield, MO, 65804, United States
2.3k from Lester E. Cox Medical Center South center

AC, Breakfast Included, Business Services, Crib, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Hot Tub

8.6

Fabulous

1003 reviews

$124
Average price / night
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Hilton Garden Inn Springfield, MO
Hilton Garden Inn Springfield, MO
Hotel
4155 S Nature Center Way, Springfield, MO, 65804, United States
2.7k from Lester E. Cox Medical Center South center

AC, Bar, Breakfast Available, Business Services, Crib, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

9.0

Fabulous

836 reviews

$144
Average price / night
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La Quinta by Wyndham Springfield South
La Quinta by Wyndham Springfield South
Hotel
Lester E. Cox Medical Center South, Springfield, Missouri, USA
2.8k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Family

8.2

Very Good

626 reviews

$94
Average price / night
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La Quinta Inn & Suites by Wyndham Springfield South
La Quinta Inn & Suites by Wyndham Springfield South
Hotel
2535 S Campbell Ave, Springfield, MO, 65807, United States
2.8k from Lester E. Cox Medical Center South center

AC, Bar, Breakfast Included, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Heater

8.8

Fabulous

1004 reviews

$108
Average price / night
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TownePlace Suites Springfield
TownePlace Suites Springfield
Hotel
2009 South National Avenue, Springfield, MO, 65807, United States
3.5k from Lester E. Cox Medical Center South center

AC, Bar, Breakfast Included, Business Services, Crib, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

9.2

Superb

626 reviews

$131
Average price / night
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TownePlace Suites by Marriott Springfield
TownePlace Suites by Marriott Springfield
Hotel
Springfield, MO, USA
3.5k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Marriott , 3-star, Lodgings, Places to stay, Self-catering

8.3

Very Good

88 reviews

$140
Average price / night
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Battlefield Inn Springfield
Battlefield Inn Springfield
Hotel
2114 South Glenstone Avenue, Springfield, MO, 65804, United States
3.6k from Lester E. Cox Medical Center South center

AC, Free Parking, Frontdesk 24 Hour, Heater, Housekeeping, Internet, Microwave, No Smoking, TV

5.0

Review score

329 reviews

$62
Average price / night
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Extended Stay America Select Suites - Springfield - South - Battlefield
Extended Stay America Select Suites - Springfield - South - Battlefield
Hotel
2021 W Kingsley St, Springfield, MO, 65807, United States
3.7k from Lester E. Cox Medical Center South center

AC, Elevator, Free Parking, Internet, Kitchen, Laundry, Living Area, Microwave, No Smoking

6.4

Good

510 reviews

$96
Average price / night
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Quality Inn & Suites Chesterfield Village
Quality Inn & Suites Chesterfield Village
Hotel
Lester E. Cox Medical Center South, Springfield, Missouri, USA
3.8k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Pet-friendly, Lodgings, Places to stay

7.7

Good

215 reviews

$82
Average price / night
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Bass Pro Shops Angler's Lodge
Bass Pro Shops Angler's Lodge
Hotel
Springfield, MO, USA
4.3k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Pet-friendly, 4-star, Lodgings, Hot tubs, Places to stay

8.1

Very Good

400 reviews

$159
Average price / night
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Lamplighter Inn-South
Lamplighter Inn-South
Hotel
Springfield, MO, USA
4.3k from Lester E. Cox Medical Center South center

Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

5.6

Review score

484 reviews

$78
Average price / night
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Vīb Best Western Springfield
Vīb Best Western Springfield
Hotel
Springfield, MO, USA
4.3k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Parking, 4-star, Lodgings, Places to stay, Family, Accessible hotels

8.7

Fabulous

302 reviews

$107
Average price / night
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Days Inn by Wyndham Battlefield Rd/Hwy 65
Days Inn by Wyndham Battlefield Rd/Hwy 65
Hotel
Springfield, MO, USA
4.7k from Lester E. Cox Medical Center South center

Accommodations, Pools, Parking, Lodgings, Places to stay, Accessible hotels

7.2

Good

432 reviews

$91
Average price / night
Check Availability
Quality Inn US65 & E Battlefield Rd Springfield
Quality Inn US65 & E Battlefield Rd Springfield
Hotel
Springfield, MO, USA
4.9k from Lester E. Cox Medical Center South center

B&bs, Cheap, Accommodations, Parking, Inns, Pet-friendly, Lodgings, Places to stay, Accessible hotels

7.6

Good

199 reviews

$77
Average price / night
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Baymont by Wyndham Springfield South Hwy 65
Baymont by Wyndham Springfield South Hwy 65
Hotel
Springfield, MO, USA
4.9k from Lester E. Cox Medical Center South center

Cheap, Accommodations, Pools, Parking, Spa, 3-star, Lodgings, Hot tubs, Places to stay

7.6

Good

1095 reviews

$76
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Hotels in Lester E. Cox Medical Center South.

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Lester E. Cox Medical Center South Hotels on the Map

Frequently Asked Questions

You can explore 64 verified hotels in Lester E. Cox Medical Center South. These include a range of options from luxury resorts and boutique hotels to budget-friendly accommodations suitable for different travel styles.

Hotel prices in Lester E. Cox Medical Center South vary depending on the season, location, and property type. Rates typically start from around $62 per night, with higher prices for premium hotels, central locations, or peak travel dates.

Most hotels in Lester E. Cox Medical Center South include amenities such as Accessibility, Wheelchair Accessible, and Guest Services. Additional features like breakfast, parking, or resort facilities may vary by property, so it’s helpful to review the details before booking.

You can identify top-rated hotels in Lester E. Cox Medical Center South by sorting listings based on guest ratings and reviews. Looking at recent feedback, overall scores, and review volume can help you find properties that consistently deliver a high-quality experience.

For popular travel periods or busy locations, booking 30 to 60 days in advance is generally recommended to secure preferred options. During quieter periods, you may find more flexibility and availability closer to your travel dates.

Yes, some hotels in Lester E. Cox Medical Center South welcome pets. Currently, 18 listings allow pets, although policies may vary. It’s a good idea to review any pet-related rules before booking.

Many hotels in Lester E. Cox Medical Center South offer flexible or refundable booking options. Checking the cancellation policy before confirming your reservation can help you choose a rate that suits your travel plans.