Hotels in Heart of Chicago, IL: Compare 10+ Sites & Save

AirbnbBooking.comVrboExpediaKayakTripadvisorHotels.comAgoda.com
  1. VBOR
  2. Hotels
  3.  USA

  4.  Illinois

  5.  Chicago
  6.  Heart of Chicago

Refine your search

Price per night

Amenity Filter

Rating

594 Best Hotels in Heart of Chicago (Starting from $80)

Hampton Inn & Suites Chicago Medical District Uic
Hampton Inn & Suites Chicago Medical District Uic
Hotel
Chicago, IL, USA
2.8k from Heart of Chicago center

Cheap, Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay

9.2

Superb

152 reviews

$237
Average price / night
Check Availability
Designer Retreat 2BR w Cowboy Pool, Fire Pit  & Fast Access
Designer Retreat 2BR w Cowboy Pool, Fire Pit & Fast Access
Hotel
Chicago, IL, 60608, United States
1.6k from Heart of Chicago center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Laundry, Microwave, No Smoking

New to Booking
$467
Average price / night
Check Availability
Hyatt House Chicago Medical/University District
Hyatt House Chicago Medical/University District
Hotel
Chicago, IL, USA
2.9k from Heart of Chicago center

Accommodations, Parking, Pet-friendly, 4-star, Lodgings, Places to stay, Accessible hotels

8.5

Very Good

953 reviews

$196
Average price / night
Check Availability
The Neighborhood Hotel - Little Italy One Bedroom
The Neighborhood Hotel - Little Italy One Bedroom
Hotel
Chicago, IL, 60607-4625, United States
2.6k from Heart of Chicago center

AC, Dryer, Elevator, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking

9.6

Exceptional

4 reviews

$358
Average price / night
Check Availability
Hyatt Place Chicago Medical/University District
Hyatt Place Chicago Medical/University District
Hotel
Chicago, IL, USA
2.9k from Heart of Chicago center

Accommodations, Parking, Pet-friendly, 4-star, Lodgings, Places to stay, Accessible hotels

8.4

Very Good

1534 reviews

$235
Average price / night
Check Availability
Courtyard by Marriott Chicago at Medical District-UIC
Courtyard by Marriott Chicago at Medical District-UIC
Hotel
Chicago, IL, USA
3.0k from Heart of Chicago center

Accommodations, Parking, Marriott , 3-star, Lodgings, Places to stay, Family, Accessible hotels

8.5

Very Good

148 reviews

$264
Average price / night
Check Availability
Hotel Chicago West Loop, SureStay Collection by Best Western
Hotel Chicago West Loop, SureStay Collection by Best Western
Hotel
Chicago, IL, USA
3.4k from Heart of Chicago center

Accommodations, Parking, Pet-friendly, Lodgings, Places to stay, Accessible hotels

7.4

Good

952 reviews

$1436
Average price / night
Check Availability
Chinatown Hotel Chicago
Chinatown Hotel Chicago
Hotel
Chicago, IL, USA
3.6k from Heart of Chicago center

Accommodations, Lodgings, Places to stay

5.6

Review score

1181 reviews

$80
Average price / night
Check Availability
SpringHill Suites by Marriott Chicago Chinatown
SpringHill Suites by Marriott Chicago Chinatown
Hotel
Chicago, IL, USA
3.6k from Heart of Chicago center

Cheap, Accommodations, Parking, 3-star, Lodgings, Places to stay, Family, Self-catering, Accessible hotels

9.0

Fabulous

658 reviews

$212
Average price / night
Check Availability
Chicago South Loop Hotel
Chicago South Loop Hotel
Hotel
Chicago, IL, USA
4.0k from Heart of Chicago center

Accommodations, Parking, 3-star, Lodgings, Places to stay, Family, Accessible hotels

6.2

Good

2723 reviews

$119
Average price / night
Check Availability
Jaslin Hotel
Jaslin Hotel
Hotel
261 West Cermak Rd, Chicago, IL, 60616, United States
3.5k from Heart of Chicago center

AC, Elevator, Fitness Equipment, Frontdesk 24 Hour, Internet, No Smoking, TV

9.0

Fabulous

1201 reviews

$125
Average price / night
Check Availability
Holiday Inn Hotel & Suites Chicago - Downtown by IHG
Holiday Inn Hotel & Suites Chicago - Downtown by IHG
Hotel
Chicago, IL, USA
4.2k from Heart of Chicago center

Accommodations, Pools, Parking, Holiday inn , 3-star, Lodgings, Places to stay, Accessible hotels

8.2

Very Good

555 reviews

$197
Average price / night
Check Availability
Hyatt House Chicago West Loop-Fulton Market
Hyatt House Chicago West Loop-Fulton Market
Hotel
Chicago, IL, USA
4.3k from Heart of Chicago center

Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Family, Accessible hotels

8.4

Very Good

531 reviews

$322
Average price / night
Check Availability
Crowne Plaza - Chicago West Loop by IHG
Crowne Plaza - Chicago West Loop by IHG
Hotel
Chicago, IL, USA
4.4k from Heart of Chicago center

Accommodations, Parking, Romantic, Pet-friendly, 3-star, Lodgings, Beach, Places to stay, Family

8.4

Very Good

620 reviews

$166
Average price / night
Check Availability
Skyline 2BR in South Loop Chicago Near McCormick Place & Soldier Field
Skyline 2BR in South Loop Chicago Near McCormick Place & Soldier Field
Hotel
Chicago, IL, 60616, United States
4.2k from Heart of Chicago center

AC, Barbecue, Dryer, Elevator, Fitness Equipment, Free Parking, Heater, Internet, Laundry

New to Booking
$560
Average price / night
Check Availability
Hampton Inn Chicago McCormick Place
Hampton Inn Chicago McCormick Place
Hotel
Chicago, IL, USA
4.4k from Heart of Chicago center

Cheap, Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

8.4

Very Good

788 reviews

$184
Average price / night
Check Availability
Modern 2BR w/ Skyline View  Near McCormick & Park
Modern 2BR w/ Skyline View Near McCormick & Park
Hotel
Chicago, IL, 60616, United States
4.2k from Heart of Chicago center

AC, Barbecue, Dryer, Elevator, Fitness Equipment, Free Parking, Heater, Internet, Kitchen

7.0

Good

2 reviews

$488
Average price / night
Check Availability
Hilton Garden Inn Chicago McCormick Place
Hilton Garden Inn Chicago McCormick Place
Hotel
Chicago, IL, USA
4.4k from Heart of Chicago center

Accommodations, Pools, Parking, Hilton , Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

8.0

Good

334 reviews

$161
Average price / night
Check Availability
Holiday Inn & Suites Chicago - Downtown by IHG
Holiday Inn & Suites Chicago - Downtown by IHG
Hotel
506 West Harrison Street, Chicago, IL, 60607, United States
4.2k from Heart of Chicago center

AC, Breakfast Available, Business Services, Crib, Elevator, Fitness Equipment, Frontdesk 24 Hour, Grocery, Internet

8.6

Fabulous

1011 reviews

$150
Average price / night
Check Availability
Home2 Suites By Hilton Chicago McCormick Place
Home2 Suites By Hilton Chicago McCormick Place
Hotel
Chicago, IL, USA
4.4k from Heart of Chicago center

Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

8.9

Fabulous

272 reviews

$258
Average price / night
Check Availability
Chic Cozy 2BR near McCormick + Museum Campus
Chic Cozy 2BR near McCormick + Museum Campus
Hotel
Chicago, IL, 60616, United States
4.3k from Heart of Chicago center

AC, Barbecue, Dryer, Elevator, Fitness Equipment, Free Parking, Heater, Internet, Kitchen

New to Booking
$497
Average price / night
Check Availability
Marriott Marquis Chicago
Marriott Marquis Chicago
Hotel
Chicago, IL, USA
4.6k from Heart of Chicago center

Accommodations, Parking, Marriott , 4-star, Lodgings, Places to stay, Family, Accessible hotels

8.4

Very Good

350 reviews

$445
Average price / night
Check Availability
LIVN - West Loop Chicago
LIVN - West Loop Chicago
Hotel
555 West Jackson Boulevard, Chicago, IL, 60661, United States
4.3k from Heart of Chicago center

AC, Elevator, Fitness Equipment, Internet, Kitchen, Laundry, Living Area, Microwave, No Smoking

10.0

Exceptional

5 reviews

$118
Average price / night
Check Availability
Nobu Hotel Chicago
Nobu Hotel Chicago
Hotel
Heart of Chicago, Chicago, Illinois, USA
4.6k from Heart of Chicago center

Luxury, Accommodations, Pools, Parking, Pet-friendly, 5-star, Lodgings, Places to stay, Accessible hotels

8.9

Fabulous

428 reviews

$440
Average price / night
Check Availability
Budget-Friendly Stay and Free Coffee Downtown
Budget-Friendly Stay and Free Coffee Downtown
Hotel
Chicago, IL, USA
4.7k from Heart of Chicago center

Accommodations, Lodgings, Places to stay

New to Booking
$196
Average price / night
Check Availability
Hyatt House Chicago West Loop
Hyatt House Chicago West Loop
Hotel
105 N MAY STREET, Chicago, IL, 60607, United States
4.3k from Heart of Chicago center

AC, Bar, Barbecue, Breakfast Included, Business Services, Elevator, Fitness Equipment, Frontdesk 24 Hour, Grocery

9.0

Fabulous

1219 reviews

$258
Average price / night
Check Availability
Hyatt Regency McCormick Place Chicago
Hyatt Regency McCormick Place Chicago
Hotel
Chicago, IL, USA
4.7k from Heart of Chicago center

Accommodations, Pools, Parking, Romantic, 4-star, Lodgings, Places to stay, Family, Accessible hotels

8.3

Very Good

833 reviews

$1495
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Hotels in Heart of Chicago.

Where to stay in Heart of Chicago? Best neighborhoods & areas

Stay Near Heart of Chicago's Top Attractions

VacationByOwnerRentals can help you find hotels, resorts, and rentals near many of 's top attractions, neighborhoods, and points of interest.

Heart of Chicago Hotels on the Map

Frequently Asked Questions

You can explore 594 verified hotels in Heart of Chicago. These include a range of options from luxury resorts and boutique hotels to budget-friendly accommodations suitable for different travel styles.

Hotel prices in Heart of Chicago vary depending on the season, location, and property type. Rates typically start from around $80 per night, with higher prices for premium hotels, central locations, or peak travel dates.

Most hotels in Heart of Chicago include amenities such as Accessibility, Wheelchair Accessible, and Guest Services. Additional features like breakfast, parking, or resort facilities may vary by property, so it’s helpful to review the details before booking.

You can identify top-rated hotels in Heart of Chicago by sorting listings based on guest ratings and reviews. Looking at recent feedback, overall scores, and review volume can help you find properties that consistently deliver a high-quality experience.

For popular travel periods or busy locations, booking 30 to 60 days in advance is generally recommended to secure preferred options. During quieter periods, you may find more flexibility and availability closer to your travel dates.

Yes, some hotels in Heart of Chicago welcome pets. Currently, 32 listings allow pets, although policies may vary. It’s a good idea to review any pet-related rules before booking.

Many hotels in Heart of Chicago offer flexible or refundable booking options. Checking the cancellation policy before confirming your reservation can help you choose a rate that suits your travel plans.