Hotels in Duke Medicine, NC: Compare 10+ Sites & Save

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  6.  Duke Medicine

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196 Best Hotels in Duke Medicine (Starting from $67)

Fairfield Inn & Suites Raleigh-Durham Airport/Brier Creek
Fairfield Inn & Suites Raleigh-Durham Airport/Brier Creek
Hotel
Durham, NC, USA
1.1k from Duke Medicine center

Cheap, Accommodations, Pools, Parking, Romantic, 3-star, Lodgings, Places to stay

8.4

Very Good

154 reviews

$120
Average price / night
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The Westin Raleigh-Durham Airport
The Westin Raleigh-Durham Airport
Hotel
Raleigh, NC, USA
1.2k from Duke Medicine center

Luxury, Cheap, Accommodations, Pools, Parking, Pet-friendly, 4-star, Lodgings, Places to stay

9.2

Superb

88 reviews

$278
Average price / night
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Aloft Raleigh Durham Airport Brier Creek
Aloft Raleigh Durham Airport Brier Creek
Hotel
Raleigh, NC, USA
1.3k from Duke Medicine center

Cheap, Accommodations, Pools, Parking, Romantic, Pet-friendly, 3-star, Lodgings, Places to stay

8.5

Very Good

414 reviews

$156
Average price / night
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Hyatt House Raleigh / RDU / Brier Creek
Hyatt House Raleigh / RDU / Brier Creek
Hotel
10030 Sellona St, Raleigh, NC, 27617, United States
1.3k from Duke Medicine center

AC, Airport Transportation, Bar, Barbecue, Breakfast Included, Business Services, Elevator, Fitness Equipment, Free Parking

9.2

Superb

1002 reviews

$133
Average price / night
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Residence Inn Raleigh-Durham Airport/Brier Creek
Residence Inn Raleigh-Durham Airport/Brier Creek
Hotel
Raleigh, NC, USA
1.7k from Duke Medicine center

Cheap, Accommodations, Pools, Parking, Romantic, Pet-friendly, 3-star, Lodgings, Places to stay

9.0

Fabulous

127 reviews

$174
Average price / night
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Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG
Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG
Hotel
10450 Little Brier Creek Ln, Raleigh, NC, 27617, United States
1.6k from Duke Medicine center

AC, Airport Transportation, Breakfast Included, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Internet

8.8

Fabulous

961 reviews

$130
Average price / night
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Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
Hotel
Raleigh, NC, USA
1.7k from Duke Medicine center

Accommodations, Pools, Parking, Boutique, Hilton , Pet-friendly, 4-star, Lodgings, Places to stay

9.0

Fabulous

633 reviews

$200
Average price / night
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Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
Hotel
8021 Arco Corporate Drive, Raleigh, NC, 27617, United States
1.7k from Duke Medicine center

AC, Airport Transportation, Breakfast Included, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Housekeeping

9.4

Superb

1005 reviews

$132
Average price / night
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Courtyard by Marriott Raleigh-Durham Airport/Brier Creek
Courtyard by Marriott Raleigh-Durham Airport/Brier Creek
Hotel
Raleigh, NC, USA
1.8k from Duke Medicine center

Cheap, Accommodations, Pools, Parking, Romantic, Marriott , 3-star, Lodgings, Places to stay

8.8

Fabulous

366 reviews

$186
Average price / night
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Courtyard Raleigh-Durham Airport/Brier Creek
Courtyard Raleigh-Durham Airport/Brier Creek
Hotel
10600 Little Brier Creek Lane, Raleigh, NC, 27617, United States
1.8k from Duke Medicine center

AC, Airport Transportation, Bar, Breakfast Available, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

9.2

Superb

980 reviews

$148
Average price / night
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Cambria Hotel Raleigh-Durham Airport
Cambria Hotel Raleigh-Durham Airport
Hotel
Morrisville, NC, USA
4.3k from Duke Medicine center

Accommodations, Parking, 3-star, Lodgings, Places to stay, Accessible hotels

7.1

Good

311 reviews

$97
Average price / night
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Tru by Hilton Raleigh Durham Airport
Tru by Hilton Raleigh Durham Airport
Hotel
350 Airgate Dr, Morrisville, NC, 27560, United States
4.3k from Duke Medicine center

AC, Airport Transportation, Arcade, Breakfast Included, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

9.2

Superb

1005 reviews

$116
Average price / night
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Hyatt Place Raleigh Durham Airport
Hyatt Place Raleigh Durham Airport
Hotel
Morrisville, NC, USA
4.4k from Duke Medicine center

Accommodations, Parking, Pet-friendly, 4-star, Lodgings, Places to stay, Family, Accessible hotels

7.7

Good

575 reviews

$124
Average price / night
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Country Inn & Suites by Radisson Raleigh-Durham Airport NC
Country Inn & Suites by Radisson Raleigh-Durham Airport NC
Hotel
Morrisville, NC, USA
4.5k from Duke Medicine center

Cheap, Accommodations, Parking, Romantic, 3-star, Lodgings, Places to stay, Family, Accessible hotels

8.0

Good

1186 reviews

$103
Average price / night
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SpringHill Suites Raleigh-Durham Airport/Research Triangle Park
SpringHill Suites Raleigh-Durham Airport/Research Triangle Park
Hotel
Durham, NC, USA
4.7k from Duke Medicine center

Cheap, Accommodations, Parking, 3-star, Lodgings, Places to stay, Accessible hotels

8.0

Good

175 reviews

$110
Average price / night
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Near RDU Airport + Free Shuttle, Pool, & Dining
Near RDU Airport + Free Shuttle, Pool, & Dining
Hotel
Durham, NC, 27703, United States
4.7k from Duke Medicine center

AC, Breakfast Available, Elevator, Fitness Equipment, Free Parking, Heater, Internet, Living Area, No Smoking

New to Booking
$1197
Average price / night
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Sleep Inn Raleigh Durham Airport
Sleep Inn Raleigh Durham Airport
Hotel
Duke Medicine, Raleigh, North Carolina, USA
4.8k from Duke Medicine center

B&bs, Accommodations, Parking, Inns, Romantic, 3-star, Lodgings, Places to stay, Accessible hotels

6.9

Good

306 reviews

$81
Average price / night
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Minutes to Research Triangle + Free Shuttle & Pool
Minutes to Research Triangle + Free Shuttle & Pool
Hotel
Durham, NC, 27703, United States
4.7k from Duke Medicine center

AC, Breakfast Available, Elevator, Fitness Equipment, Free Parking, Heater, Internet, Living Area, No Smoking

New to Booking
$1155
Average price / night
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Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park
Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park
Hotel
Durham, NC, USA
4.8k from Duke Medicine center

Cheap, Accommodations, Pools, Parking, Sheraton, Pet-friendly, 3-star, Lodgings, Places to stay

8.5

Very Good

105 reviews

$144
Average price / night
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Sheraton Imperial Hotel Raleigh-Durham Airport/RTP
Sheraton Imperial Hotel Raleigh-Durham Airport/RTP
Hotel
4700 Emperor Blvd, Durham, NC, 27703, United States
4.8k from Duke Medicine center

AC, Airport Transportation, Bar, Breakfast Available, Business Services, Crib, Elevator, Extra Bed, Fitness Equipment

8.6

Fabulous

948 reviews

$139
Average price / night
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Microtel Inn by Wyndham Raleigh-Durham Airport
Microtel Inn by Wyndham Raleigh-Durham Airport
Hotel
Morrisville, NC, USA
4.8k from Duke Medicine center

Cheap, Accommodations, Parking, Lodgings, Places to stay, Accessible hotels

7.8

Good

948 reviews

$67
Average price / night
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SpringHill Suites by Marriott Raleigh-Durham Airport/Research Triangle Park
SpringHill Suites by Marriott Raleigh-Durham Airport/Research Triangle Park
Hotel
920 Slater Rd, Durham, NC, 27703, United States
4.8k from Duke Medicine center

AC, Airport Transportation, Breakfast Included, Business Services, Crib, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

8.2

Very Good

1001 reviews

$129
Average price / night
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Marriott Raleigh Durham Research Triangle Park
Marriott Raleigh Durham Research Triangle Park
Hotel
Durham, NC, USA
4.9k from Duke Medicine center

Cheap, Accommodations, Parking, Marriott , 3-star, Lodgings, Places to stay, Family, Accessible hotels

7.7

Good

75 reviews

$233
Average price / night
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DoubleTree by Hilton Raleigh Durham Airport at Research Triangle Park
DoubleTree by Hilton Raleigh Durham Airport at Research Triangle Park
Hotel
Durham, NC, USA
4.9k from Duke Medicine center

Cheap, Accommodations, Pools, Parking, 4-star, Lodgings, Places to stay, Family, Accessible hotels

8.5

Very Good

312 reviews

$129
Average price / night
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Fairfield by Marriott Inn & Suites Durham
Fairfield by Marriott Inn & Suites Durham
Hotel
Durham, NC, USA
5.0k from Duke Medicine center

Accommodations, Lodgings, Places to stay

New to Booking
$134
Average price / night
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Sonesta Select Raleigh Durham Airport Morrisville
Sonesta Select Raleigh Durham Airport Morrisville
Hotel
Morrisville, NC, USA
5.0k from Duke Medicine center

Cheap, Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

8.2

Very Good

360 reviews

$128
Average price / night
Check Availability
Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park
Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park
Hotel
Durham, NC, USA
5.0k from Duke Medicine center

Cheap, Accommodations, Parking, Boutique, 3-star, Lodgings, Places to stay, Accessible hotels

9.1

Superb

263 reviews

$179
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Hotels in Duke Medicine.

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Frequently Asked Questions

You can explore 196 verified hotels in Duke Medicine. These include a range of options from luxury resorts and boutique hotels to budget-friendly accommodations suitable for different travel styles.

Hotel prices in Duke Medicine vary depending on the season, location, and property type. Rates typically start from around $67 per night, with higher prices for premium hotels, central locations, or peak travel dates.

Most hotels in Duke Medicine include amenities such as Accessibility, Wheelchair Accessible, and Guest Services. Additional features like breakfast, parking, or resort facilities may vary by property, so it’s helpful to review the details before booking.

You can identify top-rated hotels in Duke Medicine by sorting listings based on guest ratings and reviews. Looking at recent feedback, overall scores, and review volume can help you find properties that consistently deliver a high-quality experience.

For popular travel periods or busy locations, booking 30 to 60 days in advance is generally recommended to secure preferred options. During quieter periods, you may find more flexibility and availability closer to your travel dates.

Yes, some hotels in Duke Medicine welcome pets. Currently, 29 listings allow pets, although policies may vary. It’s a good idea to review any pet-related rules before booking.

Many hotels in Duke Medicine offer flexible or refundable booking options. Checking the cancellation policy before confirming your reservation can help you choose a rate that suits your travel plans.