Hotels in Depew, NY: Compare 10+ Sites & Save

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90 Best Hotels in Depew (Starting from $70)

Buffalo Airport Hotel
Buffalo Airport Hotel
Hotel
Cheektowaga, NY, USA
2.8k from Depew center

Accommodations, Parking, 3-star, Lodgings, Places to stay, Accessible hotels

7.4

Good

488 reviews

$111
Average price / night
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Aloft Buffalo Airport
Aloft Buffalo Airport
Hotel
Cheektowaga, NY, USA
2.9k from Depew center

Cheap, Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

8.2

Very Good

254 reviews

$143
Average price / night
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Comfort Inn & Suites Buffalo Airport
Comfort Inn & Suites Buffalo Airport
Hotel
4345 Genesee St, Buffalo, NY, 14225, United States
2.8k from Depew center

AC, Airport Transportation, Breakfast Included, Crib, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Housekeeping

8.2

Very Good

1302 reviews

$119
Average price / night
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The Delavan Hotel
The Delavan Hotel
Hotel
Depew, New York, USA
2.9k from Depew center

Cheap, Accommodations, Parking, Spa, Romantic, 4-star, Lodgings, Places to stay, Family

8.7

Fabulous

614 reviews

$171
Average price / night
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TownePlace Suites Buffalo Airport
TownePlace Suites Buffalo Airport
Hotel
4265 Genesee St, Buffalo, NY, 14225, United States
2.8k from Depew center

AC, Airport Transportation, Barbecue, Breakfast Included, Crib, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

9.0

Fabulous

817 reviews

$173
Average price / night
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Fairfield Inn & Suites – Buffalo Airport
Fairfield Inn & Suites – Buffalo Airport
Hotel
Cheektowaga, NY, USA
2.9k from Depew center

Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Hot tubs, Places to stay, Accessible hotels

8.2

Very Good

215 reviews

$176
Average price / night
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The Delavan Hotel & Spa
The Delavan Hotel & Spa
Hotel
6461 Transit Road, Bowmansville, NY, 14043, United States
2.9k from Depew center

AC, Airport Transportation, Bar, Breakfast Available, Business Services, Crib, Elevator, Extra Bed, Fitness Equipment

9.0

Fabulous

1007 reviews

$146
Average price / night
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Courtyard by Marriott Buffalo Airport
Courtyard by Marriott Buffalo Airport
Hotel
Cheektowaga, NY, USA
2.9k from Depew center

Cheap, Accommodations, Pools, Parking, Boutique, Marriott , Pet-friendly, 3-star, Lodgings

8.4

Very Good

215 reviews

$242
Average price / night
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Fairfield Inn & Suites by Marriott Buffalo Airport
Fairfield Inn & Suites by Marriott Buffalo Airport
Hotel
4271 Genesee Street, Buffalo, NY, 14225, United States
2.9k from Depew center

AC, Airport Transportation, Barbecue, Breakfast Included, Business Services, Elevator, Extra Bed, Fitness Equipment, Free Parking

8.6

Fabulous

1002 reviews

$137
Average price / night
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Courtyard Buffalo Airport
Courtyard Buffalo Airport
Hotel
4243 Genesee St, Buffalo, NY, 14225, United States
3.0k from Depew center

AC, Airport Transportation, Bar, Breakfast Available, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

9.0

Fabulous

1001 reviews

$153
Average price / night
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Sleep Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport
Hotel
Depew, New York, USA
3.0k from Depew center

Accommodations, Parking, Spa, 3-star, Lodgings, Hot tubs, Places to stay, Accessible hotels

7.2

Good

706 reviews

$97
Average price / night
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Quality Inn Buffalo Airport
Quality Inn Buffalo Airport
Hotel
Cheektowaga, NY, USA
3.0k from Depew center

B&bs, Accommodations, Inns, 3-star, Lodgings, Places to stay, Accessible hotels

3.6

Review score

155 reviews

$78
Average price / night
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Hilton Garden Inn Buffalo Airport
Hilton Garden Inn Buffalo Airport
Hotel
4201 Genesee St, Buffalo, NY, 14225, United States
3.1k from Depew center

AC, Airport Transportation, Bar, Breakfast Available, Business Services, Crib, Elevator, Fitness Equipment, Free Parking

9.0

Fabulous

1001 reviews

$138
Average price / night
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Suburban Studios Buffalo Airport
Suburban Studios Buffalo Airport
Hotel
Cheektowaga, NY, USA
3.0k from Depew center

Transportation/Shuttle, Guest Services, Business Services, Air Conditioner, Security/Safety, Parking, Smoking

6.5

Good

117 reviews

$80
Average price / night
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Hampton Inn & Suites Buffalo Airport
Hampton Inn & Suites Buffalo Airport
Hotel
133 Buell Avenue, Buffalo, NY, 14225, United States
3.3k from Depew center

AC, Airport Transportation, Breakfast Included, Business Services, Crib, Elevator, Extra Bed, Fitness Equipment, Free Parking

8.0

Good

1002 reviews

$144
Average price / night
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Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Hotel
131 Buell Ave, Buffalo, NY, 14225, United States
3.3k from Depew center

AC, Airport Transportation, Breakfast Included, Business Services, Crib, Elevator, Extra Bed, Fitness Equipment, Frontdesk 24 Hour

8.2

Very Good

1004 reviews

$137
Average price / night
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Holiday Inn Express & Suites Buffalo Airport by IHG
Holiday Inn Express & Suites Buffalo Airport by IHG
Hotel
Cheektowaga, NY, USA
3.4k from Depew center

Accommodations, Pools, Parking, Holiday inn , Lodgings, Places to stay, Accessible hotels

7.4

Good

356 reviews

$157
Average price / night
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Homewood Suites by Hilton Buffalo Airport
Homewood Suites by Hilton Buffalo Airport
Hotel
760 Dick Rd, Buffalo, NY, 14225, United States
3.4k from Depew center

AC, Airport Transportation, Barbecue, Breakfast Included, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour

8.4

Very Good

1002 reviews

$156
Average price / night
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Extended Stay America Suites - Buffalo - Airport
Extended Stay America Suites - Buffalo - Airport
Hotel
901 Dick Rd, Buffalo, NY, 14225, United States
3.4k from Depew center

AC, Breakfast Included, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Internet, Kitchen, Laundry

7.0

Good

1033 reviews

$94
Average price / night
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Baymont by Wyndham Buffalo
Baymont by Wyndham Buffalo
Hotel
3475 Union Rd, Buffalo, NY, 14225, United States
3.9k from Depew center

AC, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Housekeeping, Internet, Laundry, Microwave

7.6

Good

986 reviews

$99
Average price / night
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Garden Place Hotel
Garden Place Hotel
Hotel
6615 Transit Road, Buffalo, NY, 14221, United States
4.0k from Depew center

AC, Airport Transportation, Breakfast Available, Business Services, Elevator, Fitness Equipment, Free Parking, Frontdesk 24 Hour, Housekeeping

7.6

Good

2346 reviews

$90
Average price / night
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HomeTowne Studios by Red Roof Buffalo - Niagara Airport
HomeTowne Studios by Red Roof Buffalo - Niagara Airport
Hotel
146 Maple Drive, Building B, Bowmansville, NY, 14026, United States
4.1k from Depew center

AC, Free Parking, Frontdesk 24 Hour, Heater, Housekeeping, Internet, Kitchen, Microwave, Pets

6.4

Good

39 reviews

$70
Average price / night
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La Quinta Inn by Wyndham Buffalo Airport
La Quinta Inn by Wyndham Buffalo Airport
Hotel
6619 Transit Rd, Buffalo, NY, 14221, United States
4.1k from Depew center

AC, Airport Transportation, Bar, Breakfast Included, Business Services, Crib, Elevator, Fitness Equipment, Free Parking

8.0

Good

1480 reviews

$88
Average price / night
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Red Roof Inn Buffalo - Niagara Airport
Red Roof Inn Buffalo - Niagara Airport
Hotel
146 Maple Drive Building A, Bowmansville, NY, 14026, United States
4.1k from Depew center

AC, Free Parking, Frontdesk 24 Hour, Internet, Pets

7.2

Good

1000 reviews

$73
Average price / night
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Salvatores Grand Hotel
Salvatores Grand Hotel
Hotel
Williamsville, NY, USA
4.4k from Depew center

Accommodations, Parking, Romantic, 3-star, Lodgings, Places to stay, Family

9.1

Superb

494 reviews

$182
Average price / night
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Home2 Suites By Hilton Williamsville Buffalo Airport
Home2 Suites By Hilton Williamsville Buffalo Airport
Hotel
Depew, New York, USA
4.4k from Depew center

Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Family, Accessible hotels

8.1

Very Good

103 reviews

$143
Average price / night
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Motel 6-Buffalo, NY - Airport - Williamsville
Motel 6-Buffalo, NY - Airport - Williamsville
Hotel
Williamsville, NY, USA
4.4k from Depew center

Accommodations, Pools, Parking, Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

5.2

Review score

442 reviews

$77
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Hotels in Depew.

Stay Near Depew's Top Attractions

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Depew Hotels on the Map

Frequently Asked Questions

You can explore 90 verified hotels in Depew. These include a range of options from luxury resorts and boutique hotels to budget-friendly accommodations suitable for different travel styles.

Hotel prices in Depew vary depending on the season, location, and property type. Rates typically start from around $70 per night, with higher prices for premium hotels, central locations, or peak travel dates.

Most hotels in Depew include amenities such as Accessibility, Wheelchair Accessible, and Guest Services. Additional features like breakfast, parking, or resort facilities may vary by property, so it’s helpful to review the details before booking.

You can identify top-rated hotels in Depew by sorting listings based on guest ratings and reviews. Looking at recent feedback, overall scores, and review volume can help you find properties that consistently deliver a high-quality experience.

For popular travel periods or busy locations, booking 30 to 60 days in advance is generally recommended to secure preferred options. During quieter periods, you may find more flexibility and availability closer to your travel dates.

Yes, some hotels in Depew welcome pets. Currently, 26 listings allow pets, although policies may vary. It’s a good idea to review any pet-related rules before booking.

Many hotels in Depew offer flexible or refundable booking options. Checking the cancellation policy before confirming your reservation can help you choose a rate that suits your travel plans.