Family-Friendly Vacation Rentals in Santo Spirito, Florence: Compare 10+ Sites & Save

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  3.  Italy
  4.  Tuscany
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  6.  Santo Spirito

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5767 Best Family Vacation Rentals in Santo Spirito (Starting from $161)

Villino in San Frediano
Villino in San Frediano
Apartment
Florence, Italy
0.2k from Santo Spirito center

Apartments, Cheap, Accommodations, Lodgings, Vacation rentals, Places to stay, Family, Self-catering

2 Bedrooms5 Guests
9.5

Superb

18 reviews

$291
Average price / night
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Bellosguardo / San Francesco di Paola with private garden
Bellosguardo / San Francesco di Paola with private garden
Apartment
Firenze, 50124, Italy
0.3k from Santo Spirito center

AC, Heater, Internet, Kitchen, Laundry, Microwave, No Smoking, Outdoor Space, Patio

3 Bedrooms5 Guests
10.0

Exceptional

213 reviews

$172
Average price / night
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Celeste Apartment-San Frediano
Celeste Apartment-San Frediano
Apartment
Florence, Italy
0.2k from Santo Spirito center

Apartments, Cheap, Accommodations, Lodgings, Places to stay, Family, Self-catering

1 Bedroom5 Guests
9.0

Fabulous

62 reviews

$184
Average price / night
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Beautiful Apartment in the Historic City Centre of Florence
Beautiful Apartment in the Historic City Centre of Florence
Apartment
Firenze, 50124, Italy
0.3k from Santo Spirito center

AC, Balcony, Extra Bed, Heater, Internet, Kitchen, Laundry, Living Area, Microwave

2 Bedrooms6 Guests
9.8

Exceptional

63 reviews

$209
Average price / night
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Exquisite 2BR apartment nearby Borgo San Frediano
Exquisite 2BR apartment nearby Borgo San Frediano
Apartment
Florence, Italy
0.2k from Santo Spirito center

Apartments, Accommodations, Lodgings, Places to stay, Self-catering

2 Bedrooms4 Guests
7.0

Good

14 reviews

$394
Average price / night
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Nice apartment for 4 people with WIFI and TV
Nice apartment for 4 people with WIFI and TV
Apartment
Florence, 50142, Italy
0.4k from Santo Spirito center

Crib, Heater, Internet, Kitchen, Laundry, Living Area, Microwave, TV, Washer

2 Bedrooms4 Guests
New to Booking
$259
Average price / night
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Private Jacuzzi - Villa Bellosguardo in Florence Historic Center
Private Jacuzzi - Villa Bellosguardo in Florence Historic Center
Villa
Florence, Italy
0.2k from Santo Spirito center

Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Jacuzzis, Places to stay

3 Bedrooms8 Guests
8.0

Good

2 reviews

$818
Average price / night
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Merville House Central Florence
Merville House Central Florence
Apartment
Firenze, 50126, Italy
0.5k from Santo Spirito center

AC, Balcony, Extra Bed, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

1 Bedroom4 Guests
9.8

Exceptional

53 reviews

$165
Average price / night
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Burchiello Chic Stay-With Green View In Quiet Florence
Burchiello Chic Stay-With Green View In Quiet Florence
Apartment
Florence, Italy
0.2k from Santo Spirito center

Apartments, Accommodations, Parking, Lodgings, Places to stay

2 Bedrooms5 Guests
New to Booking
$309
Average price / night
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PSFAPT- Comfort just a few steps from the center of Florence
PSFAPT- Comfort just a few steps from the center of Florence
Apartment
Firenze, 50143, Italy
0.5k from Santo Spirito center

AC, Crib, Dryer, Free Parking, Heater, Hot Tub, Internet, Kitchen, Laundry

4 Bedrooms7 Guests
9.8

Exceptional

136 reviews

$310
Average price / night
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San Frediano Sunset Apartment
San Frediano Sunset Apartment
Apartment
Florence, Italy
0.2k from Santo Spirito center

Apartments, Accommodations, Lodgings, Places to stay

1 Bedroom6 Guests
New to Booking
$175
Average price / night
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Apartment set in a property with breathtaking view of Florence!
Apartment set in a property with breathtaking view of Florence!
Apartment
Firenze, 50124, Italy
0.5k from Santo Spirito center

AC, Balcony, Crib, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry

2 Bedrooms4 Guests
9.4

Superb

6 reviews

$473
Average price / night
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Casa Vittoria by Mmega
Casa Vittoria by Mmega
Apartment
Santo Spirito, Florence, Italy
0.2k from Santo Spirito center

Apartments, Accommodations, Lodgings, Vacation rentals, Places to stay, Self-catering

2 Bedrooms4 Guests
7.3

Good

6 reviews

$207
Average price / night
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La Piccola Corte - Sweet Dreams in Florence
La Piccola Corte - Sweet Dreams in Florence
Apartment
Firenze, 50124, Italy
0.5k from Santo Spirito center

AC, Barbecue, Crib, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms5 Guests
9.0

Fabulous

6 reviews

$509
Average price / night
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Berni
Berni
Apartment
Florence, Italy
0.3k from Santo Spirito center

Apartments, Cheap, Accommodations, Pet-friendly, Lodgings, Places to stay

1 Bedroom2 Guests
9.3

Superb

3 reviews

$225
Average price / night
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San Frediano Real Estate +PARKING
San Frediano Real Estate +PARKING
Apartment
Firenze, 50143, Italy
0.5k from Santo Spirito center

AC, Crib, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

1 Bedroom4 Guests
New to Booking
$282
Average price / night
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Aleardi Roof Apartment by Mamo Florence
Aleardi Roof Apartment by Mamo Florence
Apartment
Florence, Italy
0.3k from Santo Spirito center

Apartments, Cheap, Accommodations, Parking, Lodgings, Places to stay, Self-catering

2 Bedrooms7 Guests
8.7

Fabulous

71 reviews

$382
Average price / night
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2 bedroom apartment in florence
2 bedroom apartment in florence
Apartment
Firenze, 50143, Italy
0.6k from Santo Spirito center

AC, Dryer, Heater, Internet, Kitchen, Laundry, Living Area, Microwave, No Smoking

2 Bedrooms6 Guests
9.4

Superb

6 reviews

$161
Average price / night
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Bice & Krizia Apartments by Mamo Florence
Bice & Krizia Apartments by Mamo Florence
Apartment
Florence, Italy
0.3k from Santo Spirito center

Apartments, Cheap, Accommodations, Parking, Lodgings, Places to stay, Self-catering

3 Bedrooms12 Guests
9.2

Superb

122 reviews

$198
Average price / night
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Chiara Apartment , San Frediano Florence
Chiara Apartment , San Frediano Florence
Apartment
Florence, 50142, Italy
0.6k from Santo Spirito center

Crib, Heater, Internet, Kitchen, Laundry, Living Area, Microwave, TV, Washer

2 Bedrooms4 Guests
New to Booking
$230
Average price / night
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Il Cortile di Viola
Il Cortile di Viola
Apartment
Italy
0.3k from Santo Spirito center

Apartments, Cheap, Accommodations, Lodgings, Places to stay, Family, Self-catering

2 Bedrooms4 Guests
8.8

Fabulous

10 reviews

$214
Average price / night
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Panoramic Penthouse on the Arno-Florence
Panoramic Penthouse on the Arno-Florence
Apartment
Firenze, 50124, Italy
0.6k from Santo Spirito center

AC, Balcony, Crib, Dryer, Elevator, Heater, Internet, Kitchen, Laundry

3 Bedrooms6 Guests
9.8

Exceptional

88 reviews

$560
Average price / night
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Luxury Historic apartment with Terrace in central Florence • Oltrarno
Luxury Historic apartment with Terrace in central Florence • Oltrarno
Apartment
Firenze, 50124, Italy
0.6k from Santo Spirito center

AC, Crib, Heater, Internet, Kitchen, Laundry, Living Area, Microwave, No Smoking

2 Bedrooms4 Guests
9.8

Exceptional

125 reviews

$228
Average price / night
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charming villa with panoramic view of Florence
charming villa with panoramic view of Florence
Villa
Firenze, 50124, Italy
0.6k from Santo Spirito center

AC, Barbecue, Extra Bed, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave

1 Bedroom4 Guests
New to Booking
$547
Average price / night
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Dimora Pieri - Corsini Apartment, historic building  in the old center with lift and terrace
Dimora Pieri - Corsini Apartment, historic building in the old center with lift and terrace
Apartment
Firenze, 50125, Italy
0.7k from Santo Spirito center

AC, Elevator, Heater, Internet, Living Area, Microwave, No Smoking, TV

1 Bedroom3 Guests
10.0

Exceptional

1 reviews

$254
Average price / night
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Dimora Pieri - Ginori Apartment, historic building in the old center with elevator and terrace/balcony
Dimora Pieri - Ginori Apartment, historic building in the old center with elevator and terrace/balcony
Apartment
Firenze, 50125, Italy
0.7k from Santo Spirito center

AC, Balcony, Elevator, Heater, Internet, Kitchen, Living Area, Microwave, No Smoking

2 Bedrooms4 Guests
New to Booking
$324
Average price / night
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Dimora Pieri - Appartamento Medici, historic building  in the old center with elevator
Dimora Pieri - Appartamento Medici, historic building in the old center with elevator
Apartment
Firenze, 50125, Italy
0.7k from Santo Spirito center

AC, Elevator, Heater, Internet, Living Area, Microwave, No Smoking, TV

3 Bedrooms6 Guests
10.0

Exceptional

1 reviews

$436
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Family Vacation Rentals in Santo Spirito.

Stay Near Santo Spirito's Top Attractions

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Santo Spirito Family Vacation Rentals on the Map

Frequently Asked Questions

You can explore 5767 verified family-friendly vacation rentals in Santo Spirito. These include spacious homes, villas, and condos designed to accommodate families of different sizes.

Prices for family-friendly rentals in Santo Spirito vary depending on the season, number of bedrooms, and included amenities. Rates typically start from around $161 per night, with larger homes and peak travel periods often costing more.

Many family-friendly rentals in Santo Spirito offer baby-friendly items such as high chairs, cribs, or pack-and-play options. Availability can vary, so it’s helpful to check the listing details before booking.

Yes, some rentals in Santo Spirito are well suited for multi-generational stays, offering multiple bedrooms, separate living areas, and enough space for larger groups to stay comfortably together.

For busy travel periods such as school holidays or summer breaks, booking 90 to 120 days in advance is recommended to secure the best options. Availability may be more flexible during quieter times of the year.

Family-friendly rentals in Santo Spirito often include amenities such as Child Friendly, Internet, and Fireplace/Heating. These features help make stays more convenient and enjoyable for both adults and children.

You can use search filters to find rentals that offer features like game rooms, playgrounds, or entertainment areas. Checking property descriptions can also help you identify homes that are well suited for families with children.