Family-Friendly Vacation Rentals in Matlacha Isles, FL: Compare 10+ Sites & Save

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1487 Best Family Vacation Rentals in Matlacha Isles (Starting from $180)

Waterfront Bungalow with Pool and Bikes in Matlacha
Waterfront Bungalow with Pool and Bikes in Matlacha
House
Matlacha, FL, USA
0.1k from Matlacha Isles center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

3 Bedrooms8 Guests
10.0

Exceptional

1 reviews

$240
Average price / night
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Beautiful Matlacha Isles direct access waterfront home with dock, lift and deck
Beautiful Matlacha Isles direct access waterfront home with dock, lift and deck
House
Matlacha, FL, 33991, United States
0.1k from Matlacha Isles center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Hot Tub, Internet, Kitchen

3 Bedrooms7 Guests
10.0

Exceptional

55 reviews

$296
Average price / night
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Heated Pool and Lanai Matlacha Isles Getaway
Heated Pool and Lanai Matlacha Isles Getaway
House
Matlacha, FL, USA
0.1k from Matlacha Isles center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals, Places to stay

3 Bedrooms6 Guests
New to Booking
$257
Average price / night
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Heated Pool + Lanai: Matlacha Isles Getaway
Heated Pool + Lanai: Matlacha Isles Getaway
House
Matlacha Isles, FL, 33991, United States
0.1k from Matlacha Isles center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms6 Guests
9.4

Superb

20 reviews

$380
Average price / night
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Water View Wonder
Water View Wonder
House
Matlacha, FL, USA
0.2k from Matlacha Isles center

Accommodations, Pools, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Vacation rentals, Places to stay

3 Bedrooms8 Guests
New to Booking
$219
Average price / night
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Dog-friendly waterfront home with heated pool, lanai, central AC, & W/D
Dog-friendly waterfront home with heated pool, lanai, central AC, & W/D
House
Matlacha Isles, FL, 33991, United States
0.2k from Matlacha Isles center

AC, Barbecue, Dryer, Free Parking, Kitchen, Laundry, Living Area, Microwave, No Smoking

3 Bedrooms8 Guests
10.0

Exceptional

16 reviews

$252
Average price / night
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Villa Lahaina your perfect tropical getaway
Villa Lahaina your perfect tropical getaway
House
Cape Coral, FL, USA
0.5k from Matlacha Isles center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

3 Bedrooms6 Guests
New to Booking
$435
Average price / night
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Welcome to Villa Lahaina – your perfect tropical getaway
Welcome to Villa Lahaina – your perfect tropical getaway
Villa
Cape Coral, FL, 33991, United States
0.5k from Matlacha Isles center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Microwave

3 Bedrooms6 Guests
10.0

Exceptional

1 reviews

$307
Average price / night
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BIG WATER VIEW!, Heated Saltwater Pool and Spa - Villa Manatees Crossing - Roelens
BIG WATER VIEW!, Heated Saltwater Pool and Spa - Villa Manatees Crossing - Roelens
House
Matlacha, FL, USA
0.7k from Matlacha Isles center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Hot tubs, Places to stay

4 Bedrooms8 Guests
New to Booking
$192
Average price / night
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Charming 4-bedroom villa with AC &Heated Saltwater Pool in peaceful Cape Coral
Charming 4-bedroom villa with AC &Heated Saltwater Pool in peaceful Cape Coral
Villa
Cape Coral, FL, 33991, United States
0.5k from Matlacha Isles center

AC, Barbecue, Dryer, Fireplace, Free Parking, Heater, Internet, Kitchen, Laundry

4 Bedrooms8 Guests
10.0

Exceptional

2 reviews

$273
Average price / night
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Charming, Comfort and Relaxation Await! - Casa Bella - Roelens
Charming, Comfort and Relaxation Await! - Casa Bella - Roelens
House
Matlacha, FL, USA
0.8k from Matlacha Isles center

Security/Safety, Parking, Spa, View, Accessibility, Barbecue/Outdoor Cooking, Internet

1 Bedroom8 Guests
New to Booking
$180
Average price / night
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Entire home in Matlacha Isles-Matlacha, Florida\n4 guests 2 bedrooms 3 beds
Entire home in Matlacha Isles-Matlacha, Florida\n4 guests 2 bedrooms 3 beds
House
Matlacha Isles-Matlacha Shores, FL, 33991, United States
0.6k from Matlacha Isles center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry, Living Area

2 Bedrooms4 Guests
10.0

Exceptional

2 reviews

$250
Average price / night
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Villa Neptune's Grotto- BRAND NEW with heated Pool, Hot Tub, and dock with Tiki
Villa Neptune's Grotto- BRAND NEW with heated Pool, Hot Tub, and dock with Tiki
House
Matlacha, FL, USA
0.9k from Matlacha Isles center

Cheap, Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals

3 Bedrooms6 Guests
8.7

Fabulous

3 reviews

$357
Average price / night
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Villa Lago Vista - Waterfront Gem w/ Gulf Access
Villa Lago Vista - Waterfront Gem w/ Gulf Access
Villa
CAPE CORAL, FL, 33991, United States
0.6k from Matlacha Isles center

AC, Arcade, Barbecue, Crib, Dryer, Extra Bed, Free Parking, Heater, Hot Tub

4 Bedrooms8 Guests
10.0

Exceptional

39 reviews

$390
Average price / night
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Lakefront Home with Private Dock in Cape Coral!
Lakefront Home with Private Dock in Cape Coral!
House
Matlacha, FL, USA
1.0k from Matlacha Isles center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Hot tubs, Places to stay

4 Bedrooms13 Guests
New to Booking
$364
Average price / night
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VRCC Villa Paradisio
VRCC Villa Paradisio
Villa
Cape Coral, FL, 33991, United States
0.6k from Matlacha Isles center

AC, Balcony, Barbecue, Dryer, Free Parking, Heater, Hot Tub, Internet, Kitchen

4 Bedrooms12 Guests
9.6

Exceptional

11 reviews

$459
Average price / night
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119 Old Burnt Store
119 Old Burnt Store
House
Matlacha, FL, USA
1.3k from Matlacha Isles center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

4 Bedrooms8 Guests
New to Booking
$281
Average price / night
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Amazing sunsets, Fishing from the dock, Large lanai & Pool -  Villa Boa Vista - Roelens Vacations
Amazing sunsets, Fishing from the dock, Large lanai & Pool - Villa Boa Vista - Roelens Vacations
House
Cape Coral, FL, 33993, United States
0.6k from Matlacha Isles center

AC, Barbecue, Crib, Dryer, Heater, Internet, Kitchen, Laundry, Living Area

3 Bedrooms6 Guests
10.0

Exceptional

4 reviews

$281
Average price / night
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New listing - Amazing new 3beds/3baths Gulf access villa w. heated pool and outdoor kitchen!
New listing - Amazing new 3beds/3baths Gulf access villa w. heated pool and outdoor kitchen!
Villa
Matlacha, FL, USA
1.3k from Matlacha Isles center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay, Family

3 Bedrooms6 Guests
New to Booking
$411
Average price / night
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GULF ACCESS & BIG WATER VIEW!, Heated Saltwater Pool  and Spa -  Villa Manatees Crossing - Roelens
GULF ACCESS & BIG WATER VIEW!, Heated Saltwater Pool and Spa - Villa Manatees Crossing - Roelens
House
Cape Coral, FL, 33991, United States
0.7k from Matlacha Isles center

AC, Barbecue, Crib, Dryer, Extra Bed, Free Parking, Heater, Hot Tub, Internet

4 Bedrooms11 Guests
9.0

Fabulous

2 reviews

$393
Average price / night
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Little EsCape
Little EsCape
House
Matlacha, FL, USA
1.3k from Matlacha Isles center

Accommodations, Pools, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

3 Bedrooms7 Guests
New to Booking
$245
Average price / night
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Exclusive Deal: Luxury Water Jewel featuring Private Boat & Spa
Exclusive Deal: Luxury Water Jewel featuring Private Boat & Spa
House
Cape Coral, FL, 33991, United States
0.7k from Matlacha Isles center

AC, Barbecue, Crib, Dryer, Free Parking, Hot Tub, Internet, Kitchen, Laundry

4 Bedrooms9 Guests
9.4

Superb

23 reviews

$538
Average price / night
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Cape Coral Villa 1001: Private Pool Tranquil Stay
Cape Coral Villa 1001: Private Pool Tranquil Stay
House
Matlacha, FL, USA
1.3k from Matlacha Isles center

Accommodations, Pools, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay, Accessible hotels

4 Bedrooms8 Guests
New to Booking
$284
Average price / night
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PRIVATE VACATION HOME Cape Coral w/ Heated Saltwater Pool - Spa -Gas Grill
PRIVATE VACATION HOME Cape Coral w/ Heated Saltwater Pool - Spa -Gas Grill
Villa
Cape Coral, FL, 33991, United States
0.8k from Matlacha Isles center

AC, Barbecue, Dryer, Free Parking, Heater, Hot Tub, Internet, Kitchen, Laundry

3 Bedrooms6 Guests
10.0

Exceptional

26 reviews

$279
Average price / night
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Fun Gulf-Access Retreat with Heated Pool, Dock & Tiki Hut Getaway - Villa Gone Coastal - Roelens
Fun Gulf-Access Retreat with Heated Pool, Dock & Tiki Hut Getaway - Villa Gone Coastal - Roelens
House
Cape Coral, FL, 33991, United States
0.9k from Matlacha Isles center

AC, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Living Area, Microwave

4 Bedrooms8 Guests
New to Booking
$267
Average price / night
Check Availability
Kayaks, Bicycles, Pool, Gulf Access: Endless Summer Feelings
Kayaks, Bicycles, Pool, Gulf Access: Endless Summer Feelings
House
Cape Coral, FL, 33991, United States
1.0k from Matlacha Isles center

AC, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

3 Bedrooms6 Guests
10.0

Exceptional

1 reviews

$303
Average price / night
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Lakefront Home w/ Private Dock in Cape Coral!
Lakefront Home w/ Private Dock in Cape Coral!
House
Cape Coral, FL, 33991, United States
1.0k from Matlacha Isles center

AC, Barbecue, Crib, Dryer, Extra Bed, Fireplace, Fitness Equipment, Free Parking, Heater

4 Bedrooms13 Guests
10.0

Exceptional

21 reviews

$552
Average price / night
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Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Family Vacation Rentals in Matlacha Isles.

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Matlacha Isles Family Vacation Rentals on the Map

Frequently Asked Questions

You can explore 1487 verified family-friendly vacation rentals in Matlacha Isles. These include spacious homes, villas, and condos designed to accommodate families of different sizes.

Prices for family-friendly rentals in Matlacha Isles vary depending on the season, number of bedrooms, and included amenities. Rates typically start from around $180 per night, with larger homes and peak travel periods often costing more.

Many family-friendly rentals in Matlacha Isles offer baby-friendly items such as high chairs, cribs, or pack-and-play options. Availability can vary, so it’s helpful to check the listing details before booking.

Yes, some rentals in Matlacha Isles are well suited for multi-generational stays, offering multiple bedrooms, separate living areas, and enough space for larger groups to stay comfortably together.

For busy travel periods such as school holidays or summer breaks, booking 90 to 120 days in advance is recommended to secure the best options. Availability may be more flexible during quieter times of the year.

Family-friendly rentals in Matlacha Isles often include amenities such as Child Friendly, Pool, and Fireplace/Heating. These features help make stays more convenient and enjoyable for both adults and children.

You can use search filters to find rentals that offer features like game rooms, playgrounds, or entertainment areas. Checking property descriptions can also help you identify homes that are well suited for families with children.