Family-Friendly Vacation Rentals in Guana Tolomato Matanzas National Estuarine Research Reserve, FL: Compare 10+ Sites & Save

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223 Best Family Vacation Rentals in Guana Tolomato Matanzas National Estuarine Research Reserve (Starting from $505)

Hemingway Dream, 5 Bedrooms, Beach Front, Sleeps 14
Hemingway Dream, 5 Bedrooms, Beach Front, Sleeps 14
House
Ponte Vedra Beach, USA
0.3k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Air Conditioner, Internet, Parking, Oceanfront, Pet Friendly, Ocean View, View

5 Bedrooms14 Guests
New to Booking
$1678
Average price / night
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Oceanfront 5BR with Two Primary Suites + Deck
Oceanfront 5BR with Two Primary Suites + Deck
House
Ponte Vedra Beach, FL, 32082, United States
0.2k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen

5 Bedrooms10 Guests
9.8

Exceptional

60 reviews

$919
Average price / night
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PVT BeachFront with Mini Golf South Ponte Vedra Beach
PVT BeachFront with Mini Golf South Ponte Vedra Beach
House
South Ponte Vedra Beach, FL, USA
0.7k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

2 Bedrooms12 Guests
New to Booking
$859
Average price / night
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Oceanfront from Every Room! 7BR with Rooftop Deck
Oceanfront from Every Room! 7BR with Rooftop Deck
House
Ponte Vedra Beach, FL, 32082, United States
0.3k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Arcade, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet

7 Bedrooms16 Guests
8.8

Fabulous

15 reviews

$992
Average price / night
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The Beach Bum
The Beach Bum
House
Ponte Vedra Beach, FL, USA
0.9k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Accommodations, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Places to stay

1 Bedroom8 Guests
New to Booking
$808
Average price / night
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Seascape - WITH HOT TUB - Sleeps 15
Seascape - WITH HOT TUB - Sleeps 15
House
Ponte Vedra Beach, FL, 32082, United States
0.3k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Arcade, Balcony, Barbecue, Dryer, Fireplace, Free Parking, Heater, Hot Tub

5 Bedrooms15 Guests
9.8

Exceptional

156 reviews

$815
Average price / night
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Sea Haven
Sea Haven
House
Ponte Vedra Beach, FL, USA
0.9k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Places to stay

1 Bedroom12 Guests
New to Booking
$553
Average price / night
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Beachfront Rooftop Deck, Outdoor Dining + Fire Pit
Beachfront Rooftop Deck, Outdoor Dining + Fire Pit
House
Ponte Vedra Beach, FL, 32082, United States
0.3k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen

4 Bedrooms10 Guests
9.8

Exceptional

22 reviews

$923
Average price / night
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SA102 NEW Ponte Vedra Estate home
SA102 NEW Ponte Vedra Estate home
House
Ponte Vedra, FL, USA
1.2k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Accommodations, Villas, Vacation homes, Cottages, Lodgings, Places to stay

9 Bedrooms20 Guests
New to Booking
$730
Average price / night
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Oceanfront Sunrise Guana Sunset + Wraparound Porch
Oceanfront Sunrise Guana Sunset + Wraparound Porch
House
Ponte Vedra Beach, FL, 32082, United States
0.3k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Crib, Dryer, Extra Bed, Free Parking, Heater, Internet, Kitchen

3 Bedrooms8 Guests
10.0

Exceptional

6 reviews

$750
Average price / night
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New 5 Bedrooms 3 full and 2 1 2 Bathroom Oceanfro
New 5 Bedrooms 3 full and 2 1 2 Bathroom Oceanfro
House
Ponte Vedra Beach, FL, USA
1.6k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Beach, Places to stay

5 Bedrooms10 Guests
New to Booking
$506
Average price / night
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Lux BEACH FRONT 3067 S Ponte Vedra Blvd
Lux BEACH FRONT 3067 S Ponte Vedra Blvd
House
Ponte Vedra Beach, FL, 32082, United States
0.3k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

9.6

Exceptional

14 reviews

$1472
Average price / night
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White Heron Beach House
White Heron Beach House
House
Ponte Vedra, FL, USA
1.7k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Pet-friendly, Lodgings, Vacation rentals

4 Bedrooms10 Guests
7.0

Good

1 reviews

$592
Average price / night
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Beachfront 3BR with Pergola Deck and Beach Steps
Beachfront 3BR with Pergola Deck and Beach Steps
House
Ponte Vedra Beach, FL, 32082, United States
0.3k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen

3 Bedrooms6 Guests
9.6

Exceptional

7 reviews

$845
Average price / night
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New Listing Our Twilight Beach Shack - 3 BR - 2 B
New Listing Our Twilight Beach Shack - 3 BR - 2 B
House
Ponte Vedra Beach, FL, USA
1.8k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Beach, Places to stay

3 Bedrooms6 Guests
New to Booking
$523
Average price / night
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Oceanfront Escape, Grill, Hammocks, Fire Pit, & Stunning Views
Oceanfront Escape, Grill, Hammocks, Fire Pit, & Stunning Views
House
Ponte Vedra Beach, FL, 32082, United States
0.7k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

3 Bedrooms10 Guests
9.6

Exceptional

34 reviews

$769
Average price / night
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Beachside Paradise - Beautiful Remodeled home
Beachside Paradise - Beautiful Remodeled home
House
Ponte Vedra Beach, FL, USA
1.8k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Beach, Places to stay

1 Bedroom8 Guests
New to Booking
$697
Average price / night
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Coastal Luxe Estate – St. Augustine & Ponte Vedra
Coastal Luxe Estate – St. Augustine & Ponte Vedra
House
Ponte Vera Beach, FL, 32082, United States
0.8k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Crib, Dryer, Fitness Equipment, Free Parking, Heater, Internet

12 Bedrooms30 Guests
New to Booking
$2325
Average price / night
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Spacious Oceanfront Home Close to TPC and St Augustine - Immediate Availability
Spacious Oceanfront Home Close to TPC and St Augustine - Immediate Availability
House
Ponte Vedra Beach, FL, USA
2.1k from Guana Tolomato Matanzas National Estuarine Research Reserve center

Cheap, Accommodations, Parking, Villas, Vacation homes, Cottages, Lodgings, Vacation rentals, Beach

4 Bedrooms12 Guests
8.7

Fabulous

3 reviews

$850
Average price / night
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Oceanfront Getaway, Pets Allowed, WiFi, Hammocks, Space for Families and Friends
Oceanfront Getaway, Pets Allowed, WiFi, Hammocks, Space for Families and Friends
House
Ponte Vedra, FL, 32082, United States
0.9k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

4 Bedrooms8 Guests
9.8

Exceptional

10 reviews

$776
Average price / night
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Steps to Sand, Pet-Friendly Oceanfront w. Dog Run
Steps to Sand, Pet-Friendly Oceanfront w. Dog Run
House
Ponte Vedra Beach, FL, 32082, United States
0.9k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen

4 Bedrooms12 Guests
9.8

Exceptional

15 reviews

$858
Average price / night
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The Dunes House – Oceanfront Escape
The Dunes House – Oceanfront Escape
House
Ponte Vedra Beach, FL, 32082, United States
1.1k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Arcade, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet

3 Bedrooms6 Guests
9.0

Fabulous

2 reviews

$505
Average price / night
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Oceanfront 4BR Beach House in South Ponte Vedra Beach with Direct Beach Access
Oceanfront 4BR Beach House in South Ponte Vedra Beach with Direct Beach Access
House
South Ponte Vedra Beach, FL, 32082, United States
1.1k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Arcade, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet

4 Bedrooms10 Guests
New to Booking
$883
Average price / night
Check Availability
The Dunes Estate – South Ponte Vedra Beach
The Dunes Estate – South Ponte Vedra Beach
House
Ponte Vedra Beach, FL, 32082, United States
1.1k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Arcade, Balcony, Barbecue, Crib, Dryer, Extra Bed, Free Parking, Heater

6 Bedrooms14 Guests
9.6

Exceptional

65 reviews

$1101
Average price / night
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Ocean front single family home fully fenced yard!
Ocean front single family home fully fenced yard!
House
Ponte Vedra Beach, FL, 32082, United States
1.1k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Dryer, Free Parking, Heater, Internet, Kitchen, Laundry

2 Bedrooms6 Guests
9.8

Exceptional

141 reviews

$593
Average price / night
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Nautical Style Oceanfront in SPV
Nautical Style Oceanfront in SPV
House
Ponte Vedra Beach, FL, 32082, United States
1.2k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Balcony, Barbecue, Crib, Dryer, Free Parking, Heater, Internet, Kitchen

4 Bedrooms10 Guests
9.8

Exceptional

34 reviews

$869
Average price / night
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Ocean Pearl Retreat – South Ponte Vedra Beach
Ocean Pearl Retreat – South Ponte Vedra Beach
House
Ponte Vedra Beach, FL, 32082, United States
1.2k from Guana Tolomato Matanzas National Estuarine Research Reserve center

AC, Arcade, Balcony, Barbecue, Crib, Dryer, Fitness Equipment, Free Parking, Heater

3 Bedrooms6 Guests
New to Booking
$847
Average price / night
Check Availability

Other accommodation types in Guana Tolomato Matanzas National Estuarine Research Reserve:

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Family Vacation Rentals in Guana Tolomato Matanzas National Estuarine Research Reserve.

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Guana Tolomato Matanzas National Estuarine Research Reserve Family Vacation Rentals on the Map

Frequently Asked Questions

You can explore 223 verified family-friendly vacation rentals in Guana Tolomato Matanzas National Estuarine Research Reserve. These include spacious homes, villas, and condos designed to accommodate families of different sizes.

Prices for family-friendly rentals in Guana Tolomato Matanzas National Estuarine Research Reserve vary depending on the season, number of bedrooms, and included amenities. Rates typically start from around $505 per night, with larger homes and peak travel periods often costing more.

Many family-friendly rentals in Guana Tolomato Matanzas National Estuarine Research Reserve offer baby-friendly items such as high chairs, cribs, or pack-and-play options. Availability can vary, so it’s helpful to check the listing details before booking.

Yes, some rentals in Guana Tolomato Matanzas National Estuarine Research Reserve are well suited for multi-generational stays, offering multiple bedrooms, separate living areas, and enough space for larger groups to stay comfortably together.

For busy travel periods such as school holidays or summer breaks, booking 90 to 120 days in advance is recommended to secure the best options. Availability may be more flexible during quieter times of the year.

Family-friendly rentals in Guana Tolomato Matanzas National Estuarine Research Reserve often include amenities such as Child Friendly, View, and Ocean View. These features help make stays more convenient and enjoyable for both adults and children.

You can use search filters to find rentals that offer features like game rooms, playgrounds, or entertainment areas. Checking property descriptions can also help you identify homes that are well suited for families with children.