Family-Friendly Hotels in Medi Center, CA: Compare 10+ Sites & Save

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174 Best Family-Friendly Hotels in Medi Center (Starting from $58)

Good Life Resorts
Good Life Resorts
Hotel
San Diego, CA, USA
1.7k from Medi Center center

Cheap, Accommodations, Parking, Lodgings, Places to stay, Family, Self-catering

8.8

Fabulous

14 reviews

$554
Average price / night
Check Availability
Good Life Vacation Rental Resort
Good Life Vacation Rental Resort
Hotel
3209 Market St, San Diego, CA, 92102, United States
1.7k from Medi Center center

AC, Bar, Barbecue, Business Services, Free Parking, Heater, Internet, Laundry, No Smoking

9.4

Superb

34 reviews

$597
Average price / night
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Lodge at 32nd
Lodge at 32nd
Hotel
San Diego, CA, USA
1.8k from Medi Center center

Accommodations, Motels, Parking, Lodgings, Places to stay, Accessible hotels

7.2

Good

160 reviews

$69
Average price / night
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The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
Hotel
500 W Broadway, San Diego, CA, 92101, United States
5.8k from Medi Center center

AC, Bar, Breakfast Available, Business Services, Crib, Elevator, Fitness Equipment, Frontdesk 24 Hour, Grocery

9.0

Fabulous

1146 reviews

$207
Average price / night
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Quality Inn San Diego I-5 Naval Base
Quality Inn San Diego I-5 Naval Base
Hotel
San Diego, CA, USA
3.2k from Medi Center center

B&bs, Accommodations, Parking, Inns, Lodgings, Places to stay, Accessible hotels

7.4

Good

347 reviews

$104
Average price / night
Check Availability
Town and Country San Diego
Town and Country San Diego
Hotel
500 Hotel Circle North, San Diego, CA, 92108, United States
8.3k from Medi Center center

AC, Bar, Breakfast Available, Business Services, Crib, Elevator, Fitness Equipment, Frontdesk 24 Hour, Hot Tub

8.6

Fabulous

1421 reviews

$282
Average price / night
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Studio 6-National City, CA - Naval Base San Diego
Studio 6-National City, CA - Naval Base San Diego
Hotel
National City, CA, USA
3.7k from Medi Center center

Accommodations, Parking, Pet-friendly, 3-star, Lodgings, Places to stay

7.4

Good

299 reviews

$89
Average price / night
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Loews Coronado Bay Resort
Loews Coronado Bay Resort
Hotel
4000 Coronado Bay Rd, Coronado, CA, 92118, United States
9.3k from Medi Center center

AC, Babysitting, Bar, Business Services, Crib, Elevator, Fitness Equipment, Frontdesk 24 Hour, Hot Tub

8.8

Fabulous

1082 reviews

$348
Average price / night
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Rodeway Inn National City San Diego South
Rodeway Inn National City San Diego South
Hotel
National City, CA, USA
3.8k from Medi Center center

B&bs, Accommodations, Parking, Inns, Lodgings, Places to stay, Accessible hotels

7.0

Good

220 reviews

$130
Average price / night
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Howard Johnson by Wyndham National City/San Diego South
Howard Johnson by Wyndham National City/San Diego South
Hotel
National City, CA, USA
3.8k from Medi Center center

Accommodations, Lodgings, Places to stay, Accessible hotels

7.2

Good

665 reviews

$155
Average price / night
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Ramada by Wyndham San Diego National City
Ramada by Wyndham San Diego National City
Hotel
National City, CA, USA
3.9k from Medi Center center

Bar, Hot Tub, Internet, Smoking, Guest Services, Restaurant, Balcony/Terrace

6.8

Good

42 reviews

$169
Average price / night
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Holiday Inn Express San Diego South - National City by IHG
Holiday Inn Express San Diego South - National City by IHG
Hotel
National City, CA, USA
4.2k from Medi Center center

Accommodations, Pools, Parking, Holiday inn , Lodgings, Places to stay, Accessible hotels

8.8

Fabulous

251 reviews

$200
Average price / night
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Sentral Gaslamp Quarter
Sentral Gaslamp Quarter
Hotel
San Diego, CA, USA
4.6k from Medi Center center

Cheap, Accommodations, Parking, Pet-friendly, 4-star, Lodgings, Places to stay, Self-catering, Accessible hotels

8.6

Fabulous

243 reviews

$228
Average price / night
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The Davis Downtown San Diego
The Davis Downtown San Diego
Hotel
San Diego, CA, USA
4.6k from Medi Center center

Accommodations, Pet-friendly, 3-star, Lodgings, Places to stay

7.8

Good

166 reviews

$227
Average price / night
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Hotel Indigo San Diego - Gaslamp Quarter by IHG
Hotel Indigo San Diego - Gaslamp Quarter by IHG
Hotel
San Diego, CA, USA
4.7k from Medi Center center

Accommodations, Parking, Romantic, Boutique, Pet-friendly, 4-star, Lodgings, Places to stay, Family

8.7

Fabulous

687 reviews

$331
Average price / night
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Downtown San Diego Lodge
Downtown San Diego Lodge
Hotel
San Diego, CA, USA
4.7k from Medi Center center

Security/Safety, Pet Friendly, Guest Services, Air Conditioner, Internet, Fireplace/Heating, Parking

5.3

Review score

312 reviews

$171
Average price / night
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Hotel Gigi
Hotel Gigi
Hotel
San Diego, CA, USA
4.7k from Medi Center center

Accommodations, 3-star, Lodgings, Places to stay

7.7

Good

201 reviews

$275
Average price / night
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Somerset Hotel
Somerset Hotel
Hotel
San Diego, CA, USA
4.8k from Medi Center center

Balcony/Terrace, Air Conditioner, Internet, Child Friendly

New to Booking
$978
Average price / night
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Hotel Ash&9th
Hotel Ash&9th
Hotel
San Diego, CA, USA
4.8k from Medi Center center

Accommodations, Parking, Lodgings, Places to stay

5.8

Review score

1065 reviews

$125
Average price / night
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Best Western Downtown San Diego
Best Western Downtown San Diego
Hotel
San Diego, CA, USA
4.8k from Medi Center center

Accommodations, Parking, Best western , 3-star, Lodgings, Places to stay, Accessible hotels

7.7

Good

380 reviews

$239
Average price / night
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The Beau Hotel Downtown San Diego Gaslamp Quarter
The Beau Hotel Downtown San Diego Gaslamp Quarter
Hotel
San Diego, CA, USA
4.9k from Medi Center center

Cheap, Accommodations, 3-star, Lodgings, Places to stay

8.3

Very Good

159 reviews

$169
Average price / night
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Courtyard by Marriott San Diego Gaslamp/Convention Center
Courtyard by Marriott San Diego Gaslamp/Convention Center
Hotel
San Diego, CA, USA
4.9k from Medi Center center

Cheap, Accommodations, Parking, Marriott , 3-star, Lodgings, Places to stay

8.3

Very Good

302 reviews

$377
Average price / night
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Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San Diego
Hotel
San Diego, CA, USA
4.9k from Medi Center center

Accommodations, Romantic, Pet-friendly, 3-star, Lodgings, Places to stay, Accessible hotels

9.0

Fabulous

1030 reviews

$234
Average price / night
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Baymont by Wyndham San Diego Downtown
Baymont by Wyndham San Diego Downtown
Hotel
San Diego, CA, USA
4.9k from Medi Center center

Accommodations, Motels, Parking, Lodgings, Places to stay, Accessible hotels

7.4

Good

2035 reviews

$138
Average price / night
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Moxy San Diego Gaslamp Quarter
Moxy San Diego Gaslamp Quarter
Hotel
San Diego, CA, USA
4.9k from Medi Center center

Cheap, Accommodations, Parking, 4-star, Lodgings, Places to stay, Family, Accessible hotels

8.1

Very Good

606 reviews

$239
Average price / night
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Margaritaville Hotel San Diego Gaslamp Quarter
Margaritaville Hotel San Diego Gaslamp Quarter
Hotel
San Diego, CA, USA
4.9k from Medi Center center

Accommodations, Pools, Parking, Romantic, Boutique, Pet-friendly, 4-star, Lodgings, Places to stay

8.6

Fabulous

1138 reviews

$289
Average price / night
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Cortez Hill Studio
Cortez Hill Studio
Hotel
Medi Center, San Diego, California, USA
4.9k from Medi Center center

Pet Friendly, Internet, Air Conditioner, Balcony/Terrace, Kitchen, Child Friendly

8.5

Very Good

2 reviews

$58
Average price / night
Check Availability

Pro Tip:
VacationByOwnerRentals aggregates the best inventory from leading travel sites, including Booking.com, Agoda.com, Expedia.com, Vrbo.com, and Airbnb.com. Use our Advanced Filters to compare verified homes, villas, cabins, condos, cottages, vacation rentals, hotels, and eco-friendly stays. Our goal is to help you find the absolute best Family-Friendly Hotels in Medi Center.

Where to stay in Medi Center? Best neighborhoods & areas

Medi Center Family-Friendly Hotels on the Map

Frequently Asked Questions

You can explore 174 verified family-friendly hotels in Medi Center. These include kid-friendly resorts, suite-style accommodations, and hotels designed to make traveling with children more comfortable.

Prices for family-friendly hotels in Medi Center vary depending on the season, room size, and occupancy. Rates typically start from around $58 per night, with larger family suites or peak travel dates often costing more.

Many family-friendly hotels in Medi Center offer cribs, pack-and-play options, or rollaway beds upon request. Availability and fees can vary, so it’s helpful to review the property details before booking.

Yes, some hotels in Medi Center offer dedicated kids' clubs, play areas, and supervised activities. These features can help keep children entertained and give parents more flexibility during their stay.

For busy travel periods such as school holidays or summer months, it’s a good idea to book 60 to 90 days in advance to secure the best options. During quieter periods, you may find more availability closer to your travel dates.

Family-friendly hotels in Medi Center often include amenities such as Child Friendly, Guest Services, and Internet. These features are designed to make stays more convenient and comfortable for both adults and children.

Yes, some hotels in Medi Center cater to both families and pets. Currently, 26 listings allow pets, although policies may vary. You can filter your search to find accommodations that welcome both children and pets.